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34 积分 2025-10-14 加入
Identifying a New Target for BtOBP8: Discovery of a Small Amino Ketone Molecule Containing Benzothiazole Fragments
18天前
已完结
Molecularly-defined macrocycles containing azobenzene main-chain oligomers: modular stepwise synthesis, chain-length and topology-dependent properties
1个月前
已完结
Structural optimization and characterization of highly potent and selective STAT3 inhibitors for the treatment of triple negative breast cancer
1个月前
已完结
Discovery of the Highly Selective and Potent STAT3 Inhibitor for Pancreatic Cancer Treatment
1个月前
已完结
Pan-tumor activity of olomorasib, a next-generation KRAS G12C inhibitor in KRAS G12C-mutant advanced solid tumors: a first-in-human study
1个月前
已完结
Structure-Based Discovery of HS34: A Highly Selective and Orally Bioavailable CDK9 Inhibitor for Triple-Negative Breast Cancer
1个月前
已完结
Discovery of Novel and Potent Dual PARP1/ERK Inhibitors as a Promising Strategy for Cancer Therapy
1个月前
已完结
First Selective Covalent FGFR3 Inhibitors: Conquering Toxicity and Resistance
1个月前
已完结
Design and evaluation of an HSP70-targeting PROTAC in synergy with an HSF1 inhibitor for enhanced antitumor activity
3个月前
已完结
Exploiting the “Hot-Spots” of Hsp70–Bim Protein–Protein Interaction to Optimize the 1-Oxo-1H-phenalene-2,3-dicarbonitrile Analogues as Specific Hsp70–Bim Inhibitors
3个月前
已完结
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