Lv1
30 积分 2025-10-28 加入
Discovery of dual CDK4/6 and BRD4 inhibitor as apoptosis and autophagy inducers against NSCLC in vitro and in vivo
3个月前
已完结
Design, synthesis, and biological evaluation of novel CDK4/6 and BRD4 dual inhibitors for treatment of KRAS-mutant NSCLC
3个月前
已完结
Cotargeting CDK4/6 and BRD4 Promotes Senescence and Ferroptosis Sensitivity in Cancer
3个月前
已完结
Rifamycin O as a novel CRBN ligand for targeted degradation of IKZF1/3 proteins in hematopoietic malignancies
4个月前
已完结
Molecular glue degrader function of SPOP enhances STING-dependent immunotherapy efficacy in melanoma models
4个月前
已完结
Aryl-fluorosulfate-based Lysine Covalent Pan-Inhibitors of Apoptosis Protein(IAP)Antagonists with Cellular Efficacy
4个月前
已完结