Lv3
270 积分 2024-05-27 加入
Discovery and Evaluation of E0714 as an Antiepileptic Candidate: A Highly Subtype-Selective Kv7 Agonist within the Kv7 Family Designed Based on a Kv7.2-Specific Pocket
1个月前
已完结
In silico discovery and biological evaluation of a novel selective HDAC8 inhibitor featuring 1H-pyrazolo[3,4-b]pyridine scaffold
1个月前
已完结
HDAC6 inhibition enhances the anti-tumor effect of eribulin through tubulin acetylation in triple-negative breast cancer cells
3个月前
已完结
Design, synthesis and biological evaluation of coumarin-based HDAC6 inhibitors for the treatment of ulcerative colitis
4个月前
已完结
Discovery of TNI-97 as a Highly Selective, Orally Bioavailable HDAC6 Inhibitor for the Treatment of Triple-Negative Breast Cancer
4个月前
已完结
A Dual CYP17A1/HDAC6 Inhibitor for Targeted Prostate Cancer Therapy
4个月前
已完结
JBI-802: the first orally available LSD1/HDAC6 dual inhibitor to enter clinical trials
4个月前
已完结
Design, synthesis, and biological evaluation of indazole-based histone deacetylase 6 inhibitors
4个月前
已完结
Design, synthesis, and biological evaluation of HDAC6 inhibitors targeting L1 loop and serine 531 residue
4个月前
已完结
Design, synthesis, and anti-inflammatory activity characterization of novel brain-permeable HDAC6 inhibitors
4个月前
已完结