Lv6
2120 积分 2024-04-26 加入
Application of Bioisosteres in the Design and Discovery of FDA-Approved Drugs and Advanced Clinical Candidates
17天前
已完结
Design, Synthesis, and Evaluation of Novel 2,4‐disubstituted Pyrimidine Derivatives as Double Mutant Epidermal Growth Factor Receptor‐L858R/T790M Tyrosine Kinase Inhibitors
21天前
已完结
Base‐Induced Annulation of Glycal‐Derived α‐iodopyranone with 2‐Aminopyrimidinones: Access to Chiral Imidazopyrimidinones
1个月前
已关闭
Contemporary design of small-molecule kinase modulators: orthosteric, allosteric and induced-proximity strategies
1个月前
已完结
LibINVENT: Reaction-based Generative Scaffold Decoration for in Silico Library Design
1个月前
已完结
Peptidomimetics: An Overview of Recent Medicinal Chemistry Efforts toward the Discovery of Novel Small Molecule Inhibitors
1个月前
已完结
Scalable Total Synthesis of Acremolactone B
1个月前
已关闭
CS12192, a novel JAK3/JAK1/TBK1 inhibitor, attenuates autoimmune dermatoses in murine models
3个月前
已完结
On the Metabolic Stability of Fluorinated Small Molecules;A Physical Organic Chemistry Perspective
3个月前
已完结
Mitigating Heterocycle Metabolism in Drug Discovery
3个月前
已完结
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