Lv3
356 积分 2024-10-11 加入
Use of Human Dose Prediction Metrics to Enable Discovery of AZD3470, an MTA-Cooperative PRMT5 Inhibitor in Clinical Evaluation
1个月前
已完结
Scalable Atroposelective Synthesis of MRTX1719: An Inhibitor of the PRMT5/MTA Complex
1个月前
已完结
Development of novel urea-based ATM kinase inhibitors with subnanomolar cellular potency and high kinome selectivity
1个月前
已完结
The metal- and column-free synthesis of pyridin-2-yl ureas carrying cyclic secondary amine substituents and establishing the mechanism of the reactions through a computational study
1个月前
已完结
Novel 2-aminopyrimidine carboxamide derivatives as potential anti-Alzheimer's disease agents: Design, synthesis, biological activity and computational simulation evaluation
2个月前
已关闭
Palbociclib Commercial Manufacturing Process Development. Part II: Regioselective Heck Coupling with Polymorph Control for Processability
2个月前
已完结
Palbociclib Commercial Manufacturing Process Development. Part I: Control of Regioselectivity in a Grignard-Mediated SNAr Coupling
2个月前
已完结
4,5-Dihydro-1,2,4-oxadiazole as a Single Nitrogen Transfer Reagent: Synthesis of Functionalized Isoxazoles Assisted by Sc(OTf)3 or Au(I)/Sc(OTf)3 Synergistic Catalysis
3个月前
已完结
Synthesis by Substitution
3个月前
已完结
Reusable, Efficient Manganese–Copper‐Catalyzed Cross‐Coupling of Aryl Halides with Aromatic Alcohols under Solvent‐Minimized Conditions
3个月前
已完结
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