Lv1
38 积分 2025-04-12 加入
Discovery and resistance mechanism of a selective CDK12 degrader
25天前
已完结
The CIP2A-TOPBP1 axis safeguards chromosome stability and is a synthetic lethal target for BRCA-mutated cancer
1个月前
已完结
A new group of conserved coactivators that increase the specificity of AP-1 transcription factors
1个月前
已完结
Targeting p300 Reverses Acidic Microenvironment-Induced PARP Inhibitor Resistance
1个月前
已完结
Entinostat Induces Dual Apoptotic and Autophagic Cell Death in Small-Cell Lung Cancer via Epigenetic Modulation of HDAC1-p53-AMPK/mTOR Axis
1个月前
已完结
Targeting the Non-Homologous End Joining Pathway Sensitizes MDM2-Amplified Liposarcoma to Doxorubicin by Enhancing p53-Mediated Senescence
1个月前
已完结
Conformation of CD40LG and ANXA5 as Key Events of 2,7-Dibromocarbazole-Induced Cardiotoxicity Using in Vivo and in Vitro Models
1个月前
已完结
Discovery of ZJC-11 as a Novel Selective CDK7 Inhibitor for Treating Triple-Negative Breast Cancer by Inducing Cell Senescence
1个月前
已完结
Large-scale proteomic analyses of incident Alzheimer's disease reveal new pathophysiological insights and potential therapeutic targets
1个月前
已完结
Novel synaptic markers predict early tau pathology and cognitive deficit in an asymptomatic population at risk of Alzheimer's disease
1个月前
已完结