Lv31
210 积分 2024-12-27 加入
Mutant p53 protein accumulation is selectively targetable by proximity-inducing drugs
1小时前
待确认
The coming of age of cyclic peptide drugs: an update on discovery technologies
8天前
已完结
Discovery of Novel TYRO3/MERTK Dual Inhibitors
27天前
已完结
A Novel Dual-Payload ADC Platform Integrating Exatecan and Triptolide to Enhance Antitumor Efficacy and Overcome Resistance
1个月前
已完结
ZJK-807: A Selective PROTAC Degrader of KRASG12D Overcoming Resistance in Pancreatic Cancer
2个月前
已完结
A neomorphic protein interface catalyzes covalent inhibition of RAS G12D aspartic acid in tumors
4个月前
已完结
Design, Synthesis, In Vitro and In Vivo Evaluation of Cereblon Binding Bruton’s Tyrosine Kinase (BTK) Degrader CD79b targeted Antibody Drug Conjugates
5个月前
已完结
Molecular chameleons in drug discovery
6个月前
已完结
Structure-Guided Optimization of 2-Aminoquinazoline Hematopoietic Progenitor Kinase 1 Inhibitors for Improved Oral Bioavailability and Synergistic Antitumor Immunity
6个月前
已完结
Discovery of INCB159020, an Orally Bioavailable KRAS G12D Inhibitor
7个月前
已完结
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