Lv3
270 积分 2024-12-27 加入
Discovery of INCB159020, an Orally Bioavailable KRAS G12D Inhibitor
26天前
已完结
Reversible Small Molecule Multivariant Ras Inhibitors Display Tunable Affinity for the Active and Inactive Forms of Ras
1个月前
已完结
Discovery and Optimization of Pyrazine Carboxamide AZ3246, a Selective HPK1 Inhibitor
1个月前
已完结
Discovery of Elironrasib (RMC-6291), a Potent and Orally Bioavailable, RAS(ON) G12C-Selective, Covalent Tricomplex Inhibitor for the Treatment of Patients with RAS G12C-Addicted Cancers
2个月前
已完结
Dual-payload antibody–drug conjugates: Taking a dual shot
2个月前
已完结
Discovery of PF-07265028, A Selective Small Molecule Inhibitor of Hematopoietic Progenitor Kinase 1 (HPK1) for the Treatment of Cancer
3个月前
已完结
Regulated induced proximity targeting chimeras—RIPTACs—A heterobifunctional small molecule strategy for cancer selective therapies
4个月前
已完结
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