Lv2
190 积分 2024-12-27 加入
Rational Design and Identification of ISM7594 as a Tissue-Agnostic FGFR2/3 Inhibitor
1个月前
已完结
Discovery of Pyrrolopyrazine Carboxamide Derivatives as Potent and Selective FGFR2/3 Inhibitors that Overcome Mutant Resistance
1个月前
已完结
An allosteric site on cereblon
1个月前
已完结
Discovery of Novel HPK1 Inhibitors via Chemistry-Based Direct-to-Bioassay Screening and SAR Optimization
2个月前
已完结
Small Organic Carbonic Anhydrase IX Ligands from DNA-Encoded Chemical Libraries for Tumor-Targeted Delivery of Radionuclides
4个月前
已完结
Discovery of high-affinity ligands for prostatic acid phosphatase via DNA-encoded library screening enables targeted cancer therapy
4个月前
已完结
Discovery of a Series of Orally Bioavailable Androgen Receptor Degraders for the Treatment of Prostate Cancer
4个月前
已完结
Structure-Guided Development of NRAS G12D Inhibitors Based on a 5-Azaindole Core
4个月前
已完结
Discovery of AZD9750, an Orally Bioavailable Androgen Receptor Degrader for the Treatment of Prostate Cancer
4个月前
已完结
Lessons learned in linking PROTACs from discovery to the clinic
6个月前
已完结