Lv2
200 积分 2024-12-27 加入
Discovery of Novel HPK1 Inhibitors via Chemistry-Based Direct-to-Bioassay Screening and SAR Optimization
15天前
已完结
Small Organic Carbonic Anhydrase IX Ligands from DNA-Encoded Chemical Libraries for Tumor-Targeted Delivery of Radionuclides
2个月前
已完结
Discovery of high-affinity ligands for prostatic acid phosphatase via DNA-encoded library screening enables targeted cancer therapy
2个月前
已完结
Discovery of a Series of Orally Bioavailable Androgen Receptor Degraders for the Treatment of Prostate Cancer
2个月前
已完结
Structure-Guided Development of NRAS G12D Inhibitors Based on a 5-Azaindole Core
3个月前
已完结
Discovery of AZD9750, an Orally Bioavailable Androgen Receptor Degrader for the Treatment of Prostate Cancer
3个月前
已完结
Lessons learned in linking PROTACs from discovery to the clinic
4个月前
已完结
Rational Design of CDK12/13 and BRD4 Molecular Glue Degraders
4个月前
已完结
Discovery of ARD-2051 as a Potent and Orally Efficacious Proteolysis Targeting Chimera (PROTAC) Degrader of Androgen Receptor for the Treatment of Advanced Prostate Cancer
4个月前
已完结
Ring-Enlargement of in Situ Generated Cyclopropanones by the Reaction with Sulfonium Ylides: One-Pot Synthesis of Cyclobutanones
4个月前
已完结