Lv71
3530 积分 2022-07-12 加入
Mechanism of Action of KL-50, a Candidate Imidazotetrazine for the Treatment of Drug-Resistant Brain Cancers
4天前
已完结
Towards the Development of a Commercial Process To Produce Muvalaplin. Part I: Preparation of a Key Intermediate by an Evans Auxiliary-Assisted Asymmetric Alkylation
16天前
已完结
In Vitro ADME Profiling of PROTACs: Successes, Challenges, and Lessons Learned from Analysis of Clinical PROTACs from a Diverse Physicochemical Space
19天前
已完结
Discovery and Characterization of RP04340 : A Highly Potent and Orally Active Pan-KRAS PROTAC Degrader
1个月前
已完结
Predictability of Idiosyncratic Drug Toxicity Risk for Carboxylic Acid-Containing Drugs Based on the Chemical Stability of Acyl Glucuronide
1个月前
已完结
Early Process Development of a Heterobifunctional Protein Degrader
1个月前
已完结
Rapid Identification of a Potent, Selective, and Orally Active p300/CBP Bromodomain Inhibitor Bearing an Imidazo[1,2- a ]pyridine Scaffold via a Highly Efficient Four-Step Synthesis
1个月前
已完结
Discovery of BBI-355, a Potent, Selective, and Orally Available Checkpoint Kinase 1 Inhibitor for the Treatment of Extrachromosomal DNA Oncogene-Amplified Cancers
1个月前
已关闭
Synthesis of 2-Aminophenols and Heterocycles by Ru-Catalyzed C–H Mono- and Dihydroxylation
2个月前
已完结
Bicyclic Isosteres of Pyridine/Piperidine: From Synthesis to Applications
2个月前
已完结
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