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184 积分 2025-03-04 加入
Exome sequencing of hepatocellular carcinomas identifies new mutational signatures and potential therapeutic targets
18天前
已完结
A phase Ib dose-escalation study of the MEK inhibitor trametinib in combination with the PI3K/mTOR inhibitor GSK2126458 in patients with advanced solid tumors
1个月前
已完结
Synergistic anticancer efficacy of MEK inhibition and dual PI3K/mTOR inhibition in castration-resistant prostate cancer
1个月前
已完结
Generation of a double transgenic humanized neonatal Fc receptor (FcRn)/albumin mouse to study the pharmacokinetics of albumin-linked drugs
1个月前
已完结
HS-20093, a B7-H3-targeted antibody-drug conjugate in lung cancer: Results from the ARTEMIS-001 phase 1a/b trial
1个月前
已完结
A B7H3-targeting antibody–drug conjugate in advanced solid tumors: a phase 1/1b trial
1个月前
已完结
Ifinatamab deruxtecan, a B7-H3-directed antibody–drug conjugate, in patients with advanced solid tumours (IDeate-PanTumor01): dose-escalation results from a phase 1/2 trial
1个月前
已完结
BL-B01D1, a first-in-class EGFR–HER3 bispecific antibody–drug conjugate, in patients with locally advanced or metastatic solid tumours: a first-in-human, open-label, multicentre, phase 1 study
1个月前
已完结
Non-linear IV pharmacokinetics of the ATR inhibitor berzosertib (M6620) in mice
3个月前
已完结
Anti-CHI3L1 antibody suppresses colon cancer growth through downregulation of VEGFA and NAMPT expression
5个月前
已完结
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