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150 积分 2025-02-13 加入
Evolving Strategies for Previously Drugged Therapeutic Targets: Medicinal Chemistry Insights from Paradigmatic Cases
28天前
已完结
Structural determinants of integrin β-subunit specificity for latent TGF-β
1个月前
已完结
General Syntheses of Optically Active α-Trifluoromethylated Amines via Ring-Opening Reactions of N-Benzyl-2-trifluoromethylaziridine
2个月前
已完结
Discovery and preclinical evaluations of GST-HG131, a novel HBV antigen inhibitor for the treatment of chronic hepatitis B infection
2个月前
已完结
Trivalent, Gal/GalNAc-containing ligands designed for the asialoglycoprotein receptor
2个月前
已完结
Design and Synthesis of Novel Amphiphilic Dendritic Galactosides for Selective Targeting of Liposomes to the Hepatic Asialoglycoprotein Receptor
2个月前
已完结
Polyvalent Interactions in Biological Systems: Implications for Design and Use of Multivalent Ligands and Inhibitors
2个月前
已完结
Multivalent N-Acetylgalactosamine-Conjugated siRNA Localizes in Hepatocytes and Elicits Robust RNAi-Mediated Gene Silencing
2个月前
已完结
Well-Defined Multivalent Ligands for Hepatocytes Targeting via Asialoglycoprotein Receptor
2个月前
已完结
Metabolically Stable Anomeric Linkages Containing GalNAc–siRNA Conjugates: An Interplay among ASGPR, Glycosidase, and RISC Pathways
2个月前
已完结
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