Lv1
38 积分 2023-11-02 加入
Discovery of a highly potent, N-terminal domain-targeting degrader of AR-FL/AR-V7 for the treatment of prostate cancer
18天前
已完结
Discovery of BWA-522, a First-in-Class and Orally Bioavailable PROTAC Degrader of the Androgen Receptor Targeting N-Terminal Domain for the Treatment of Prostate Cancer
18天前
已完结
Molecular mechanism of substrate recognition and cleavage by human γ-secretase
1个月前
已完结
IMHB-Mediated Chameleonicity in Drug Design: A Focus on Structurally Related PROTACs
2个月前
已完结
Evaluation of Oral PROTAC Guidelines: Efflux Ratio Outweighs Chameleonicity Descriptors
2个月前
已完结
Prediction of Protein-Ligand Binding Poses via a Combination of Induced Fit Docking and Metadynamics Simulations
2个月前
已完结
Expanding the reach of molecular glue degraders
2个月前
已完结
Selective CDK2 Degradation via Noncanonical Recruitment
2个月前
已完结
Structure‐Guided Development of Selective RabGGTase Inhibitors
3个月前
已完结
A Molecular Model of the Human UDP-Glucuronosyltransferase 1A1, Its Membrane Orientation, and the Interactions between Different Parts of the Enzyme
3个月前
已完结
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