Lv1
18 积分 2023-11-02 加入
Biochemical and structural basis for differential inhibitor sensitivity of EGFR with distinct exon 19 mutations
7小时前
待确认
Discovery of Orally Efficacious Bridged Piperazines as smTNF Modulators
19天前
已完结
Structural modification aimed for improving solubility of lead compounds in early phase drug discovery
3个月前
已完结
Can Relative Binding Free Energy Predict Selectivity of Reversible Covalent Inhibitors?
6个月前
已完结
Predicting the Relative Binding Affinity for Reversible Covalent Inhibitors by Free Energy Perturbation Calculations
6个月前
已完结
Discovery of novel indoleaminopyrimidine NIK inhibitors based on molecular docking-based support vector regression (SVR) model
6个月前
已完结
Discovery of MK-1084: An Orally Bioavailable and Low-Dose KRASG12C Inhibitor
7个月前
已完结
Protein degraders push into novel target space
8个月前
已完结
Structure-Based Design and Synthesis of Potent and Selective KRAS G12D Inhibitors
9个月前
已完结
Development of Orally Efficacious Allosteric Inhibitors of TNFα via Fragment-Based Drug Design
9个月前
已完结
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