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380 积分 2025-12-31 加入
A review of FLT3 inhibitors in acute myeloid leukemia
14天前
已完结
Nintedanib is a potent FLT3 inhibitor with activity against FLT3-ITD and overcomes the gatekeeper F691L resistance mutation in acute myeloid leukemia
14天前
已完结
Small-molecule inhibitors of macrophage migration inhibitory factor (MIF) as an emerging class of therapeutics for immune disorders
23天前
已完结
Optimization of Pyrazoles as Phenol Surrogates to Yield Potent Inhibitors of Macrophage Migration Inhibitory Factor
28天前
已完结
Design, synthesis and biological evaluation of novel FXIa inhibitors featuring five-membered heterocycles as P2’ fragments
1个月前
已完结
HerTACs Enable Tumor‐Selective Lysosomal Degradation of Membrane and Extracellular Proteins via HER2 Trafficking
1个月前
已完结
Covalently targeting HSP90 with a natural small-molecule costunolide to inhibit necroptosis and ulcerative colitis
1个月前
已完结
Discovery of Furan-2-Carboxylic Acid Derivatives as Novel D-Dopachrome Tautomerase (D-DT) and Macrophage Migration Inhibitory Factor-1 (MIF-1) Dual Inhibitors
2个月前
已完结
Discovery of novel 4-azaindole derivatives as selective Nav1.2 Inhibitor with potent antiepileptic activity and low neurotoxicity
3个月前
已完结
Broadening the horizon: The promise of PROTACs in non-malignant disorders
3个月前
已完结
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