Lv3
350 积分 2024-03-11 加入
Second-Generation AURKA-Targeting PROTACs: Structural Optimization toward in Vivo Degradation in Neuroblastoma
19天前
已完结
Discovery and Characterization of Novel BLIMP-1 Heterobifunctional Ligand-Directed Degraders
19天前
已完结
Discovery of BRD9 Molecular Glue Degraders That Spare Cardiomyocytes
23天前
已完结
Structure-Based Design and Discovery of a Potent and Cell-Active LC3A/B Covalent Inhibitor
24天前
已完结
Structure-Guided Design of a Highly Selective PI3Kα Inhibitor Overcoming Metabolic Dysregulation with Potent Anti-breast Cancer Efficacy
24天前
已完结
A CRISPR activation screen identifies FBXO22 supporting targeted protein degradation
28天前
已完结
Coupling of receptor conformation and ligand orientation determine graded activity
1个月前
已完结
Structural and mechanistic insights into bisphenols action provide guidelines for risk assessment and discovery of bisphenol A substitutes
1个月前
已完结
Discovery of Novel ERα and Aromatase Dual-Targeting PROTAC Degraders to Overcome Endocrine-Resistant Breast Cancer
1个月前
已完结
Estrogen Receptor Binding Assay Method for Endocrine Disruptors Using Fluorescence Polarization
1个月前
已完结
Effect of Freeze-Thaw Cycles on Low Temperature Performance of Asphalt Mixtures
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