Lv51
832 积分 2024-03-11 加入
Design, Synthesis, and Biological Evaluation of a MyD88-Targeted Molecular Glue d21 for the Treatment of Acute Lung Injury
1小时前
待确认
Structure-Based Design of New LSD1/EGFRL858R/T790M Dual Inhibitors for Treating EGFR Mutant NSCLC Cancers
9天前
已完结
GID4-Recruiting PROTACs for BRD4 Degradation Overcome Resistance Driven by CRBN and VHL Deficiency
9天前
已完结
RIMTAC: A Novel Degrader Design Platform by Indirect VHL-Recruitment via RIPK1
9天前
已完结
Molecular Glues Recruiting RNF213 As an E3 Ligase for Targeted Protein Degradation: A Minimal Dibromoacetamide Warhead As a Recruitment Ligand
26天前
已完结
Generative Replica Exchange: A Flow-Based Framework for Accelerating Replica-Exchange Simulations
26天前
已完结
Discovery of SMD-6346: A Potent, Selective, and Orally Active SMARCA2 Degrader for Targeting SMARCA4-Deficient Human Cancers
29天前
已完结
Discovery of a Covalent Inhibitor Targeting the PHGDH Dimer Interface with Antitumor Efficacy
1个月前
已完结
Discovery of the First-in-Class Protein Arginine Methyltransferase 1 PROTAC Degrader
1个月前
已完结
Discovery of a Novel EGFR PROTAC Degrader against C797S Resistance Mutation with Potent Antitumor Efficacy in NSCLC Treatment
1个月前
已完结
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