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22 积分 2024-03-11 加入
Crystallographic Study Reveals a Cryptic Allosteric Site of FBPase by Sulfonylurea Inhibitors toward T2DM Treatment
20天前
已完结
Discovery of Potent and Brain-Penetrant Inverse Agonists for GPR61, an Orphan G Protein-Coupled Receptor
21天前
已完结
Discovery of a Potent RXRγ Degrader WCF-598 for the Treatment of Castration-Resistant Prostate Cancer
22天前
已完结
A Novel FXR-Targeted DUBTAC and Its Applications in Cholestasis Therapy
22天前
已完结
Crystallographic Study Reveals a Cryptic Allosteric Site of FBPase by Sulfonylurea Inhibitors toward T2DM Treatment
27天前
已完结
Kill Two Birds with One Stone: An Efficient and Potent AR CBS-Targeted Degrader Reverses Breast Cancer Resistance via Concurrent AR Degradation and ERα Transcriptional Suppression
27天前
已完结
Discovery of Selective and Potent Macrocyclic CDK9 Inhibitors for the Treatment of Osimertinib-Resistant Non-Small-Cell Lung Cancer
27天前
已完结
Discovery, X-ray Crystallography, and Anti-inflammatory Activity of Bromodomain-containing Protein 4 (BRD4) BD1 Inhibitors Targeting a Distinct New Binding Site
27天前
已完结
Blocking Non-enzymatic Functions by PROTAC-Mediated Targeted Protein Degradation
27天前
已完结
The protein complex crystallography beamline (BL19U1) at the Shanghai Synchrotron Radiation Facility
28天前
已完结
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