Lv4
556 积分 2025-09-22 加入
Synthesis Development of the Selective Estrogen Receptor Degrader (SERD) LSZ102 from a Suzuki Coupling to a C–H Activation Strategy
8天前
已完结
The Missing Link(er): A Roadmap to Macrocyclization in Drug Discovery
13天前
已完结
Discovery of the First-in-Class G9a/GLP Covalent Inhibitors
16天前
已完结
Concurrent Optimizations of Efficacy and Blood–Brain Barrier Permeability in New Macrocyclic LRRK2 Inhibitors for Potential Parkinson’s Disease Therapeutics
22天前
已完结
Macrocycles in Drug Discovery─Learning from the Past for the Future
22天前
已完结
Design and Synthesis of Novel Macrocyclic Derivatives as Potent and Selective Cyclin-Dependent Kinase 7 Inhibitors
22天前
已完结
Macrocyclization strategy for improving candidate profiles in medicinal chemistry
22天前
已完结
Acrylamide Bioisosterism: Alkenyl Aromatic Heterocycles as Reactivity-Tunable Warheads for Covalent BTK Inhibitors
27天前
已完结
Facile One‐Pot Transformation of Arenes into Aromatic Nitriles under Metal‐Cyanide‐Free Conditions
2个月前
已关闭
Discovery of PKMYT1 Inhibitors with a Novel Scaffold for the Treatment of Triple-Negative Breast Cancer
2个月前
已完结
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