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56 积分 2026-03-25 加入
Enhancing De Novo Designed Peptides and Proteins via Irreversible Covalent Isoquinolinium Capture
2天前
已完结
Newest glue degrader nabs multiple myeloma approval
4天前
已完结
Newest glue degrader nabs multiple myeloma approval
5天前
已关闭
Selective oestrogen receptor degrader class grows with new cancer approval
5天前
已关闭
TRI-611, a selective, brain-penetrant molecular glue degrader of ALK
9天前
已完结
Sonrotoclax overcomes BCL2 G101V mutation-induced venetoclax resistance in preclinical models of hematologic malignancy
11天前
已完结
Expanding the Repertoire for “Large Small Molecules”: Prodrug ABBV-167 Efficiently Converts to Venetoclax with Reduced Food Effect in Healthy Volunteers
13天前
已完结
ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets
13天前
已完结
Discovery of BMS-986449: A Potent, Selective Degrader of the Transcription Factors IKZF2 (Helios) and IKZF4 (Eos) to Target Regulatory T Cells in Solid Tumors
17天前
已完结
Structure-Informed Design of High-Cooperativity PROTAC Targeting SARS-CoV-2 RdRp via Click Chemistry and Enhanced Sampling Simulations
20天前
已完结
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