Lv4
518 积分 2025-01-12 加入
Drug-drug interactions that alter the exposure of glucuronidated drugs: Scope, UDP-glucuronosyltransferase (UGT) enzyme selectivity, mechanisms (inhibition and induction), and clinical significance
4小时前
待确认
Alteration of thyroid hormone homeostasis by antiepileptic drugs in humans: involvement of glucuronosyltransferase induction
5小时前
待确认
Pharmacokinetic interactions between clozapine and valproic acid in patients with treatment-resistant schizophrenia: Does UGT polymorphism affect these drug interactions?
2天前
已完结
Evaluation of the Effect of Uridine Diphosphate-Glucuronosyltransferases (UGT) Inhibition by Valproic Acid on Vixotrigine Pharmacokinetics in Healthy Volunteers
2天前
待确认
Should You Run a Dedicated TQT Study? Sponsor and Regulatory Considerations on Substitution Pathways to Assess QT Liability
26天前
已完结
A comprehensive review of 20 years of progress in nonclinical QT evaluation and proarrhythmic assessment
26天前
已完结
Innovative approaches to cardiovascular safety pharmacology assessment
26天前
已完结
A simple accurate method for concentration-QTc analysis in preclinical animal models
26天前
已关闭
Pharmacokinetic/pharmacodynamic modeling of therapeutic antibodies in oncology: current advances and future perspectives
1个月前
已完结
Recent Advances in Peptide Linkers for Antibody-Drug Conjugates
1个月前
已完结