Lv31
248 积分 2025-02-27 加入
A Scalable, Direct‐to‐Biology Platform for Accelerated Discovery of Cereblon‐Based Molecular Glue Degraders
1小时前
待确认
Structure-Informed Design of Distinct Parallel G-Quadruplex Stabilizers for KRAS-n Cancer TherapyDrive
8天前
已完结
Discovery of a novel dual-target modulator of ULK1 and ERK1/2 that suppresses triple-negative breast cancer progression and metastasis via the Exo70/Cav-1/MMPs axis
11天前
已完结
Penfluridol directly targets PDPK1 to suppress AKT1 phosphorylation and stabilize CTR1, inducing cuproptosis in colorectal cancer
13天前
已完结
Innovative anticancer molecule andrographolide: a concise review of its pharmacological targets
26天前
已完结
Landscape screening identifies the lactate-modifying enzyme AARS2 as a master regulator and therapeutic target in hepatocellular carcinoma
1个月前
已完结
A ginsenoside metabolite and its derivative target PRELID3B against lung cancer cells
1个月前
已完结
A small molecule disrupts G4–STAT1 interaction and synergizes with olaparib to drive cancer cell death
1个月前
已关闭
Overcoming ADC resistance in advanced colorectal cancer by dual targeting of TROP2 and PERK to suppress Wnt/β-catenin signaling
1个月前
已完结
Astragaloside II alleviates cardiac hypertrophy by targeting aminoacylase‐1: a novel mechanism via the β ‐catenin/transcription factor 4/ubiquitin C‐terminal hydrolase L1 axis
1个月前
已完结