Lv4
660 积分 2025-08-19 加入
Discovery of a selective CDK7 PROTAC against acute leukemia with low platelet toxicity
1个月前
已完结
Discovery of novel 2,4,5,6-tetrahydro-7H-pyrazolo[3,4-c]pyridine-7-one derivatives as PDE2 inhibitors with Alzheimer's disease therapeutic potential
4个月前
已完结
Design, synthesis, and induction of tumor ferroptosis activity of a novel FSP1 protein degrading agent
6个月前
已完结
Targeting YAP/TAZ–TEAD and Their Protein-protein Interaction for Precision Cancer Therapy
6个月前
已完结
PDE10A Inactivation Prevents Doxorubicin-Induced Cardiotoxicity and Tumor Growth
8个月前
已完结
Discovery of 3-trifluoromethyl-substituted pyrazoles as selective phosphodiesterase 10A inhibitors for orally attenuating isoprenaline-induced cardiac hypertrophy
8个月前
已完结
Key imidazolyl groups that induce phenylalanine flipping enhance the efficacy of oral BRD9 inhibitors for AML treatment
8个月前
已完结
Identification of Indoquinazoline Derivatives as Novel NR4A1 Agonists by Suppressing Adipocyte Lipogenesis for Treatment of Obesity
9个月前
已完结
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