Lv12
48 积分 2024-06-07 加入
Reaching the CNS with therapeutic oligonucleotides via TfR1: navigating delivery and distribution challenges
2小时前
求助中
An Antibody–Oligonucleotide Conjugate for Myotonic Dystrophy Type 1
1天前
已完结
A physiologically-based pharmacokinetic model to describe antisense oligonucleotide distribution after intrathecal administration
17天前
已完结
Comparative study of neuron-specific promoters in mouse brain transduced by intravenously administered AAV-PHP.eB
1个月前
已完结
Targeting the transferrin receptor to transport antisense oligonucleotides across the mammalian blood-brain barrier
2个月前
已完结
Control of phosphorothioate stereochemistry substantially increases the efficacy of antisense oligonucleotides
2个月前
已完结
Effect of 2′-O-[2-[2-(N,N-dimethylamino)ethoxy]ethyl] modification on activity of gapmer antisense oligonucleotides containing 2′,4′-constrained 2′-O-ethyl nucleic acid
2个月前
已完结
Structure and nuclease resistance of 2′,4′-constrained 2′-O-methoxyethyl (cMOE) and 2′-O-ethyl (cEt) modified DNAs
2个月前
已完结
Synthesis and Biophysical Evaluation of 2′,4′-Constrained 2′O-Methoxyethyl and 2′,4′-Constrained 2′O-Ethyl Nucleic Acid Analogues
2个月前
已完结
Design, Synthesis And Evaluation Of Constrained Methoxyethyl (cMOE) and Constrained Ethyl (cEt) Nucleoside Analogs
3个月前
已完结
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