Lv53
1258 积分 2024-06-21 加入
Structure-Based Optimization of Selective and Brain Penetrant CK1δ Inhibitors for the Treatment of Circadian Disruptions
6天前
已完结
Total Synthesis of Enlicitide Decanoate
8天前
已完结
Plasma Protein Binding as an Optimizable Parameter for In Vivo Efficacy
9天前
已完结
Discovery of Elironrasib (RMC-6291), a Potent and Orally Bioavailable, RAS(ON) G12C-Selective, Covalent Tricomplex Inhibitor for the Treatment of Patients with RAS G12C-Addicted Cancers
13天前
已完结
Discovery of Daraxonrasib (RMC-6236), a Potent and Orally Bioavailable RAS(ON) Multi-selective, Noncovalent Tri-complex Inhibitor for the Treatment of Patients with Multiple RAS-Addicted Cancers
13天前
已完结
Discovery of Pyridopyrimidinones that Selectively Inhibit the H1047R PI3Kα Mutant Protein
15天前
已完结
Targeting the PI3K/AKT/mTOR Signaling Pathway in the Treatment of Human Diseases: Current Status, Trends, and Solutions
20天前
已完结
Discovery of RP-1664: A First-in-Class Orally Bioavailable, Selective PLK4 Inhibitor
29天前
已完结
In Vitro ADME Profiling of PROTACs: Successes, Challenges, and Lessons Learned from Analysis of Clinical PROTACs from a Diverse Physicochemical Space
1个月前
已完结
Exploration of Pynaphthyridine and Binaphthyridine Manganese(I) Tricarbonyl Complexes: Influence on Carbon Dioxide Reduction Electrocatalysis
1个月前
已完结
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