Lv61
2710 积分 2024-01-08 加入
Plasma Protein Binding Determination for Unstable Ester Prodrugs: Remdesivir and Tenofovir Alafenamide
29天前
已完结
The Role of Extrahepatic Metabolism in the Pharmacokinetics of the Targeted Covalent Inhibitors Afatinib, Ibrutinib, and Neratinib
2个月前
已完结
An integrated reactive metabolite evaluation approach to assess and reduce safety risk during drug discovery and development
2个月前
已完结
Simultaneous determination of BGT-002 and its acyl glucuronide metabolite ZM326E-M2 in human plasma by liquid chromatography-tandem mass spectrometry and its application to a pharmacokinetic study
2个月前
已完结
Identification of reversible OATP1B1 and time-dependent CYP3A4 inhibition as the major risk factors for drug-induced cholestasis (DIC)
2个月前
已完结
Impact of Recovery on Fraction Unbound Using Equilibrium Dialysis
3个月前
已完结
Metabolic Disposition of Osimertinib in Rats, Dogs, and Humans: Insights into a Drug Designed to Bind Covalently to a Cysteine Residue of Epidermal Growth Factor Receptor
3个月前
已完结
A comprehensive insight on ocular pharmacokinetics
6个月前
已完结
Drug metabolizing enzymes and transporters, and their roles for the development of drug-induced liver injury
7个月前
已完结
In vitro and in vivo ADME of heterobifunctional degraders: a tailored approach to optimize DMPK properties of PROTACs©
8个月前
已完结