Lv61
2530 积分 2024-01-08 加入
The Role of Extrahepatic Metabolism in the Pharmacokinetics of the Targeted Covalent Inhibitors Afatinib, Ibrutinib, and Neratinib
1个月前
已完结
An integrated reactive metabolite evaluation approach to assess and reduce safety risk during drug discovery and development
1个月前
已完结
Simultaneous determination of BGT-002 and its acyl glucuronide metabolite ZM326E-M2 in human plasma by liquid chromatography-tandem mass spectrometry and its application to a pharmacokinetic study
1个月前
已完结
Identification of reversible OATP1B1 and time-dependent CYP3A4 inhibition as the major risk factors for drug-induced cholestasis (DIC)
1个月前
已完结
Impact of Recovery on Fraction Unbound Using Equilibrium Dialysis
1个月前
已完结
Metabolic Disposition of Osimertinib in Rats, Dogs, and Humans: Insights into a Drug Designed to Bind Covalently to a Cysteine Residue of Epidermal Growth Factor Receptor
2个月前
已完结
A comprehensive insight on ocular pharmacokinetics
4个月前
已完结
Drug metabolizing enzymes and transporters, and their roles for the development of drug-induced liver injury
5个月前
已完结
In vitro and in vivo ADME of heterobifunctional degraders: a tailored approach to optimize DMPK properties of PROTACs©
6个月前
已完结
In Vitro ADME Profiling of PROTACs: Successes, Challenges, and Lessons Learned from Analysis of Clinical PROTACs from a Diverse Physicochemical Space
6个月前
已完结
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