Lv61
1650 积分 2024-01-08 加入
Implementation of a novel method for the determination of plasma protein binding of highly bound compounds using the equilibrium dialysis method coupled with extraction to the organic phase and its comparison to known methods
1小时前
待确认
An update on the importance of plasma protein binding in drug discovery and development
1个月前
已完结
Understanding Statin‐Roxadustat Drug–Drug‐Disease Interaction Using Physiologically‐Based Pharmacokinetic Modeling
2个月前
已完结
Drug-drug interactions that alter the exposure of glucuronidated drugs: Scope, UDP-glucuronosyltransferase (UGT) enzyme selectivity, mechanisms (inhibition and induction), and clinical significance
4个月前
已完结
Plasma Protein Binding Determination for Unstable Ester Prodrugs: Remdesivir and Tenofovir Alafenamide
4个月前
已完结
Comparison of Relative Activity versus Relative Expression Factors (RAF versus REF) in Predicting Glucuronidation Mediated Drug Clearance Using Recombinant UGTs
5个月前
已完结
Orforglipron (LY3502970), a novel, oral non‐peptide glucagon‐like peptide‐1 receptor agonist: A Phase 1a, blinded, placebo‐controlled, randomized, single‐ and multiple‐ascending‐dose study in healthy participants
6个月前
已完结
Beyond CL and VSS: a comprehensive approach to human pharmacokinetic predictions
8个月前
已完结
Cabozantinib Carries the Risk of Drug-Drug Interactions via Inhibition of UDPglucuronosyltransferase (UGT) 1A9
8个月前
已完结
Comparison of commonly used and new methods to determine small molecule non-specific binding to human liver microsomes
10个月前
已完结
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