Lv61
1830 积分 2024-03-04 加入
Discovery of novel EGFR-PROTACs capable of degradation of multiple EGFR-mutated proteins
3小时前
已完结
Discovery of KT-413, a Targeted Protein Degrader of IRAK4 and IMiD Substrates Targeting MYD88 Mutant Diffuse Large B-Cell Lymphoma
4小时前
已完结
Discovery of KRAS(G12D) selective degrader ASP3082
4小时前
已完结
KT-253, A Novel MDM2 Degrader and p53 Stabilizer, Has Superior Potency and Efficacy Than MDM2 Small Molecule Inhibitors
4小时前
已完结
ACLY inhibition promotes tumour immunity and suppresses liver cancer
5天前
已完结
TEAD-targeting small molecules induce a cofactor switch to regulate the Hippo pathway
14天前
已完结
Fragment-Based Discovery and Structure-Led Optimization of MSC778, the First Potent, Selective, and Orally Bioavailable FEN1 Inhibitor
20天前
已完结
The Discovery of RP-2119: A Potent, Selective, and Orally Bioavailable Polθ ATPase Inhibitor
20天前
已完结
A Potent, Selective, Small-Molecule Inhibitor of DHX9 Abrogates Proliferation of Microsatellite Instable Cancers with Deficient Mismatch Repair
1个月前
已完结
Suppression of NRF2-dependent cancer growth by a covalent allosteric molecular glue
1个月前
已完结
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