Lv3
348 积分 2023-10-09 加入
The role of efflux and uptake transporters in [N-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine (GW572016, lapatinib) disposition and drug interactions
4小时前
求助中
Identification of selective substrates and inhibitors of the major human renal uptake transporters
5小时前
已完结
Metabolite Identification in the Preclinical and Clinical Phase of Drug Development
26天前
已完结
Mass balance study of [14C]SHR0302, a selective and potent JAK1 inhibitor in humans
1个月前
已完结
Bosentan Is a Substrate of Human OATP1B1 and OATP1B3: Inhibition of Hepatic Uptake as the Common Mechanism of Its Interactions with Cyclosporin A, Rifampicin, and Sildenafil
1个月前
已完结
Radioactive ADME Demonstrates ARV-110’s High Druggability Despite Low Oral Bioavailability
1个月前
已完结
A Phase I Study to Evaluate the Safety and Pharmacokinetics of SHR0302 Base Ointment in Healthy Adult Volunteers
1个月前
已完结
The hepatobiliary disposition of timosaponin b2 is highly dependent on influx/efflux transporters but not metabolism
3个月前
已完结
Mass balance study of [14C]SHR0302, a selective and potent JAK1 inhibitor in humans
4个月前
已完结
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