Lv1
26 积分 2023-03-22 加入
Discovery of KT-413, a Targeted Protein Degrader of IRAK4 and IMiD Substrates Targeting MYD88 Mutant Diffuse Large B-Cell Lymphoma
6天前
已完结
Confounding Factors in Targeted Degradation of Short-Lived Proteins
8天前
已完结
CC-90009: A Cereblon E3 Ligase Modulating Drug That Promotes Selective Degradation of GSPT1 for the Treatment of Acute Myeloid Leukemia
30天前
已完结
Discovery of AK-1690: A Potent and Highly Selective STAT6 PROTAC Degrader
1个月前
已完结
KRASG12D selective VHL-PROTAC with sparing KRASWT and other KRAS mutants
1个月前
已完结
Inhibition of mTOR Enhances the Efficacy of Proteasome-Dependent Targeted Protein Degradation Approaches
1个月前
已完结
Recent advances of β-catenin small molecule inhibitors for cancer therapy: Current development and future perspectives
2个月前
已完结
Targeting cancer with small molecule pan-KRAS degraders
2个月前
已完结
RanBPM, Muskelin, p48EMLP, p44CTLH, and the armadillo-repeat proteins ARMC8α and ARMC8β are components of the CTLH complex
2个月前
已完结
Discovery of Potent and Highly Selective Interleukin-2-Inducible T-Cell Kinase Degraders with In Vivo Activity
2个月前
已完结