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34 积分 2023-03-22 加入
SMAD4-dependent barrier constrains prostate cancer growth and metastatic progression
26天前
已完结
Mining the CRBN Target Space Redefines Rules for Molecular Glue-induced Neosubstrate Recognition
1个月前
已完结
Defining the human C2H2 zinc finger degrome targeted by thalidomide analogs through CRBN
1个月前
已完结
Development of dual AR/ARV7 degraders with 3,5-dimethylisoxazole to overcome antiandrogen resistance in castration-resistant prostate cancer
2个月前
已关闭
Design, synthesis, and biological evaluation of phenyl thiazole-based AR-V7 degraders
2个月前
已完结
Synthesis of an RBM39 Degrader That Downregulates CEP192 and Induces Disorganized Spindle Structures
2个月前
已完结
Discovery of KT-413, a Targeted Protein Degrader of IRAK4 and IMiD Substrates Targeting MYD88 Mutant Diffuse Large B-Cell Lymphoma
2个月前
已完结
Confounding Factors in Targeted Degradation of Short-Lived Proteins
2个月前
已完结
CC-90009: A Cereblon E3 Ligase Modulating Drug That Promotes Selective Degradation of GSPT1 for the Treatment of Acute Myeloid Leukemia
3个月前
已完结
Discovery of AK-1690: A Potent and Highly Selective STAT6 PROTAC Degrader
3个月前
已完结
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