Lv32
264 积分 2022-10-31 加入
Targeting transcriptional plasticity in cancer
5天前
已关闭
MYC/Glutamine Dependency Is a Therapeutic Vulnerability in Pancreatic Cancer with Deoxycytidine Kinase Inactivation-Induced Gemcitabine Resistance
7天前
已完结
Deoxycytidine kinase (dCK) inhibition is synthetic lethal with BRCA2 deficiency
7天前
已完结
Efficacy and safety of monlunabant in adults with obesity and metabolic syndrome: a double-blind, randomised, placebo-controlled, phase 2a trial
8天前
已完结
DualPG-DTA: A Large Language Model-Powered Graph Neural Network Framework for Enhanced Drug-Target Affinity Prediction and Discovery of Novel CDK9 Inhibitors Exhibiting in Vivo Anti-Leukemia Activity
8天前
已关闭
The Small Molecule BC-2059 Inhibits Wingless/Integrated (Wnt)-Dependent Gene Transcription in Cancer through Disruption of the Transducin β-Like 1- β-Catenin Protein Complex
8天前
已完结
E7386, a Selective Inhibitor of the Interaction between β-Catenin and CBP, Exerts Antitumor Activity in Tumor Models with Activated Canonical Wnt Signaling
8天前
已完结
Results of a phase I dose escalation and expansion study of tegavivint (BC2059), a first-in-class TBL1 inhibitor for patients with progressive, unresectable desmoid tumor
8天前
已关闭
An overview of CDK3 in cancer: clinical significance and pharmacological implications
10天前
已完结
Targeting thymine DNA glycosylase induces synthetic lethality in p53-deficient cancers
13天前
已完结
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