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88 积分 2025-08-08 加入
Fragment Screening Yields a Small‐Molecule Stabilizer of 14‐3‐3 Dimers That Modulates Client Protein Interactions
6天前
已完结
Lipophilicity and Steric Constraints Govern V-Shaped Inhibition of Human and Rat Placental 3β-Hydroxysteroid Dehydrogenase by Dialkyldimethylammonium Disinfectants: Implications for Progesterone Dysregulation
12天前
已完结
Virtual screening of Kv1.3 inhibitors and investigation of their molecular mechanisms in alleviating alcoholic liver injury in mice
13天前
已完结
SMP-656: A Self-Catalyzed Ring-Opening Hydrolysis Linker-Based ADC with Enhanced Stability and Antitumor Efficacy
13天前
已完结
Discovery of a Natural Small-Molecule Inhibitor to Novel Target STAT5A for Ischemic Stroke Therapy
14天前
已完结
Chalcone-Monoterpene Derivatives from the Buds of Cleistocalyx operculatus and Their Potential as Protein Tyrosine Phosphatase 1B Inhibitors
14天前
已完结
The Pueraria lobata-Citrus reticulata decoction ameliorates hyperuricemia by modulating urate transporters and suppressing the PI3K/AKT/NF-κB pathway
14天前
已完结
Development of High-Affinity Ligands for Human UBR2
15天前
已完结
Natural Compounds Purified from the Leaves of Aristotelia chilensis: Makomakinol, a New Alkaloid and the Effect of Aristoteline and Hobartine on NaV Channels
15天前
已完结
Informatics and Computational Approaches for the Discovery and Optimization of Natural Product-Inspired Inhibitors of the SARS-CoV-2 2′-O-Methyltransferase
15天前
已完结