Lv51
1038 积分 2024-01-30 加入
Discovery of ABBV-3373, an Anti-TNF Glucocorticoid Receptor Modulator Immunology Antibody Drug Conjugate
13天前
已完结
Development of Anti-CD74 Antibody–Drug Conjugates to Target Glucocorticoids to Immune Cells
13天前
已完结
Discovery of ABBV-154, an anti-TNF Glucocorticoid Receptor Modulator Immunology Antibody-Drug Conjugate (iADC)
18天前
已完结
DNA damage, cytotoxicity and free radical formation by mitomycin C in human cells
19天前
已完结
Mitomycin C and its analog trigger cytotoxicity in MCF-7 and K562 cancer cells through the regulation of RAS and MAPK/ERK pathways
19天前
已关闭
TDP1 represents a promising therapeutic target for overcoming tumor resistance to chemotherapeutic agents: Progress and potential
27天前
已完结
PROTACs Targeting BRM (SMARCA2) Afford Selective In Vivo Degradation over BRG1 (SMARCA4) and Are Active in BRG1 Mutant Xenograft Tumor Models
1个月前
已完结
Discovery of Orally Active Inhibitors of Brahma Homolog (BRM)/SMARCA2 ATPase Activity for the Treatment of Brahma Related Gene 1 (BRG1)/SMARCA4-Mutant Cancers
1个月前
已完结
Synthetic lethality: targeting the SMARCA2 bromodomain for degradation in SMARCA4-deficient tumors – a review of patent literature from 2019–June 2023
1个月前
已完结
SMARCA2 protein: structure, function and perspectives of drug design
1个月前
已完结
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