Lv41
444 积分 2025-03-04 加入
Discovery, Synthesis, and Biological Evaluation of 1,3,4,5-Tetrahydro-6 H -pyrano[4,3- c ]isoquinolin-6-one Derivatives as Novel and Highly Selective PARP1 Inhibitors
24天前
已完结
Discovery and Characterization of RP03707: A Highly Potent and Selective KRASG12D PROTAC
1个月前
已完结
Metabolite glues as a means of purine sensing and chemotherapeutic response
1个月前
已完结
Discovery ofLAS194046: A Potent and Selective pan-JanusKinase (JAK) Inhibitor with a Suitable Profile for Inhaled Administration
1个月前
已完结
Discovery, Synthesis, and Biological Evaluation of 1,3,4,5-Tetrahydro-6 H -pyrano[4,3- c ]isoquinolin-6-one Derivatives as Novel and Highly Selective PARP1 Inhibitors
1个月前
已完结
From Structureto Selectivity: Integrating CADD andAIDD in Rational Medicinal Chemistry Strategies for DYRK1A InhibitorDiscovery
1个月前
已完结
Discovery andCharacterization of RP04340 : A Highly Potent and OrallyActive Pan-KRAS PROTAC Degrader
1个月前
已完结
Discovery and Development of First-in-Class Cereblon-Recruiting RIPK1 Degraders
1个月前
已完结
Discovery of Highly Efficacious CRBN-Based KRAS Degraders Targeting Cancers with KRAS G12D and G12V Mutations
1个月前
已完结
Development of APH003─a Highly Potent, Selective, and Orally Bioavailable IRAK4 PROTAC Degrader for the Treatment of Inflammatory Diseases
2个月前
已完结