Lv11
50 积分 2026-04-20 加入
Discovery of Pyrazolo[1,5- a ]-1,3,5-Triazine Derivatives as Potent, Highly Selective and Orally Available Macrocyclic CDK7 Inhibitors
6小时前
已完结
Discovery of Naphthyridinone Derivatives as Selective PKMYT1/WEE1 Dual Inhibitors for Cancer Therapy
16天前
已完结
Identification of VVD-214/RO7589831, a Clinical-Stage, Covalent Allosteric Inhibitor of WRN Helicase for the Treatment of MSI-High Cancers
22天前
已完结
Targeting replication stress in cancer therapy
25天前
已完结
Adavosertib plus gemcitabine for platinum-resistant or platinum-refractory recurrent ovarian cancer: a double-blind, randomised, placebo-controlled, phase 2 trial
25天前
已完结
Discovery of Naphthyridinone Derivatives as Selective PKMYT1/WEE1 Dual Inhibitors for Cancer Therapy
1个月前
已完结
Abstract 1977: ACR-2316: A potentially first-in-class, potent, selective WEE1/PKMYT1 inhibitor rationally designed for superior single agent activity through synergistic disruption of cell cycle checkpoints
1个月前
已关闭
Induced proximity-based therapeutic modalities
1个月前
已完结
Discovery of WRN inhibitor HRO761 with synthetic lethality in MSI cancers
1个月前
已完结
Structure-Guided Discovery of Selective USP7 Inhibitors with In Vivo Activity
1个月前
已完结
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