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367 积分 2021-01-05 加入
IRAK1/4/pan-FLT3 Kinase Inhibitors with Reduced hERG Block as Treatments for Acute Myeloid Leukemia
12小时前
已完结
Antibody-Drug Conjugates of NLRP3 Agonists: How Overcoming Lysosomal Accumulation Necessitated Noncanonical Linker Attachments
12小时前
已完结
Discovery and SAR of spirochromane Akt inhibitors
1天前
已完结
Discovery of Potent PDEδ/NAMPT Dual Inhibitors: Preclinical Evaluation in KRAS Mutant Pancreatic Cancer Cells
1天前
已完结
Targeting FLT3 for treating diseases: FLT3 inhibitors
2天前
已完结
Scaffold Hopping-Based Structural Modification of Tranilast Led to the Identification of HNW005 as a Promising NLRP3 Inflammasome and URAT1 Dual Inhibitor for the Treatment of Gouty Arthritis
2天前
已完结
GNE-064: A Potent, Selective, and Orally Bioavailable Chemical Probe for the Bromodomains of SMARCA2 and SMARCA4 and the Fifth Bromodomain of PBRM1
2天前
已完结
Safety and efficacy of a selective inhibitor of cyclin-dependent kinase 9 (KB-0742) in patients with recurrent or metastatic adenoid cystic carcinoma
3天前
已完结
Design, Synthesis, and Biological Evaluation of 2,4-Diaminopyrimidine Derivatives as Potent CDK7 Inhibitors
5天前
已完结
Discovery of a Potent, Selective, and Brain-Penetrant Checkpoint Kinase 1 Inhibitor, BEN-28010, for the Treatment of Glioblastoma
5天前
已完结
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