Lv3
267 积分 2021-01-05 加入
Dual Allosteric Targeting of SHP2: Development of Bivalent Inhibitors with Enhanced Potency for Cancer Treatment
1天前
已完结
Sulfonyl Pyrazoles as Sustainable Dual Functional Group Transfer Reagents: AlCl3 Promoted Transfer of Sulfonyl and Pyrazole Groups
2天前
已完结
Development of a Direct-to-Biology Platform to Discover Potent MNK Inhibitors
2天前
已完结
PI3K Regulates Wild-type RAS Signaling to Confer Resistance to KRAS Inhibition
3天前
已完结
Discovery of N-Phenyl-4-(1H-pyrrol-3-yl)pyrimidin-2-amine Derivatives as Potent Mnk2 Inhibitors: Design, Synthesis, SAR Analysis, and Evaluation of in vitro Anti-leukaemic Activity
5天前
已完结
Pharmacologic Inhibition of MNKs in Acute Myeloid Leukemia
5天前
已完结
Design, Structure–Activity Relationships, and In Vivo Evaluation of Potent and Brain-Penetrant Imidazo[1,2-b]pyridazines as Glycogen Synthase Kinase-3β (GSK-3β) Inhibitors
7天前
已完结
Identification and Optimization of Pyridone Derivatives as Pan-MEK/RAF Nondegrading Molecular Glues for the Treatment of RAS-Driven Cancers
7天前
已完结
Octyl gallate has potent anti‐inflammasome activity by directly binding to NLRP3 LRR domain
7天前
已完结
Protein-protein interactions and related inhibitors involved in the NLRP3 inflammasome pathway
7天前
已完结
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