Lv13
55 积分 2021-01-05 加入
Optimization of a Series of Novel 1 H -Pyrrolo[3,2- c ]pyridine-Based USP1 Inhibitors with Potent In Vivo Antitumor Activity
1小时前
已完结
Rapid Two-Step Multicomponent Synthesis and Structure-degradation Relationships of Selective HDAC6 PROTAC Degraders
1小时前
求助中
A Structural Comparison of Inhibitor Binding to PKB, PKA and PKA-PKB Chimera
5小时前
已完结
Design, synthesis, and biological evaluation of N-(2-amino-phenyl)-5-(4-aryl- pyrimidin-2-yl) amino)-1H-indole-2-carboxamide derivatives as novel inhibitors of CDK9 and class I HDACs for cancer treatment
1天前
已完结
Vilazodone inhibits NLRP3 inflammasome assembly by targeting the NACHT domain and alleviates inflammatory disease
1天前
已完结
Discovery ofHighly Potent and Selective, Orally BioavailableBTK-Targeting PROTACs Featuring Novel CRBN-Binding Warheads
2天前
已完结
AI-Guided Discovery of Natural-Product-Inspired Scaffolds as Dual P-gp/BCRP Inhibitors to Overcome Cancer Multidrug Resistance
2天前
已完结
Pd-Catalyzed Cross-Coupling Reactions Promoted by Biaryl Phosphorinane Ligands
4天前
已完结
GDF15 suppresses liver inflammation independently of weight loss through neuroendocrine glucocorticoid signaling
8天前
已完结
Optimization of a Second-Generation, Highly Selective Polθ/PARP1 Dual Inhibitor with Improved Pharmacokinetics and Potent Activity against HR-Deficient Tumors
8天前
已完结
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