Lv5
911 积分 2021-01-05 加入
Design and Synthesis of PARP/CDK6 Dual-Target Inhibitors Modulating of Wnt/β-Catenin Signaling Pathway for the Treatment of BRCA Wild-Type TNBC
11小时前
已完结
Identification of a Novel Indolizine RORγT Inverse Agonist Using the AI-Driven Drug Design Platform
11小时前
已完结
Discovery of (2R)-N-[3-[2-[(3-Methoxy-1-methyl-pyrazol-4-yl)amino]pyrimidin-4-yl]-1H-indol-7-yl]-2-(4-methylpiperazin-1-yl)propenamide (AZD4205) as a Potent and Selective Janus Kinase 1 Inhibitor
11小时前
已完结
Design and Synthesis of PARP/CDK6 Dual-Target Inhibitors Modulating of Wnt/β-Catenin Signaling Pathway for the Treatment of BRCA Wild-Type TNBC
5天前
已完结
Design and synthesis of novel amide AKT1 inhibitors with selectivity over CDK2
5天前
已完结
Identification of a Novel Indolizine RORγT Inverse Agonist Using the AI-Driven Drug Design Platform
6天前
已完结
First ATG101-recruiting small molecule degrader for selective CDK9 degradation via autophagy–lysosome pathway
6天前
已完结
Innovative discovery and mechanistic validation of HyT-PD ligands for selective CDK9-targeted protein degradation
6天前
已完结
Discovery and structure-activity relationship studies of 3-pyridazinesulfonyl derivatives as a new class of inhibitors against NLRP3 inflammasome-dependent pyroptosis
6天前
已完结
SnAP-eX Reagents for the Synthesis of Exocyclic 3-Amino- and 3-Alkoxypyrrolidines and Piperidines from Aldehydes
6天前
已完结
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