Lv3
323 积分 2021-11-02 加入
XunZi, an AI biologist, reveals disease-modifying targets
4天前
已完结
Linker-Driven Sampling of PROTAC-Induced Ternary Complexes
25天前
已完结
Accelerated rational PROTAC design via deep learning and molecular simulations
25天前
已完结
Mining the CRBN target space redefines rules for molecular glue–induced neosubstrate recognition
27天前
已完结
Discovery of DN1679 as a Potent, Orally Bioavailable, and Highly Selective CDK12/13 Dual Degrader for the Treatment of Triple-Negative Breast Cancer
1个月前
已完结
Discovery of (3 R ,4 R )-15: An Advanced Factor B Inhibitor Entering Phase 3 for Complement-Mediated Diseases
1个月前
已完结
A Journey through Scaffolds: Indolines, Pyrrolidines, and Azetidines in the Quest for Inhaled DDR Inhibitors for IPF
1个月前
已完结
Discovery of Highly Selective HDAC2 Inhibitors in Cells That Elevate Histone Acetylation In Vivo without Adverse Effects from Dual Inhibition of HDAC1 and 2
1个月前
已完结
Discovery of YYSW001: A Highly Selective, Orally Bioavailable JAK1 Inhibitor Achieving Efficacy under a Moderate-Inhibition Strategy with Improved Preclinical Tolerability
1个月前
已完结
Optimization of Covalent Warhead Trajectory for KRAS G12C Active-State Inhibition
1个月前
已完结
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