Lv31
204 积分 2024-08-07 加入
Discovery of PF-06873600, a CDK2/4/6 Inhibitor for the Treatment of Cancer
3小时前
待确认
Discovery and preclinical evaluations of TQB3616, a novel CDK4-biased inhibitor
4小时前
已完结
Mechanistic Dissection of PARP1 Trapping and the Impact on In Vivo Tolerability and Efficacy of PARP Inhibitors
1个月前
已完结
Structural Basis for DNA Damage–Dependent Poly(ADP-ribosyl)ation by Human PARP-1
1个月前
已完结
The RNA-binding protein HuR in human cancer: A friend or foe?
1个月前
已完结
Discovery and Optimization of a Non-Nucleoside-Based Series of Inhibitors of 2′-Deoxynucleoside 5′-Monophosphate Glycosidase (DNPH1)
1个月前
已完结
Discovery and Characterization of Diverse Non-nucleotide Inhibitors of DNPH1 Using an Integrated Hit Finding Strategy
1个月前
已完结
A first-in-class polymerase theta inhibitor selectively targets homologous-recombination-deficient tumors
2个月前
已完结
Beyond PARP—POLθ as an anticancer target
2个月前
已完结
Discovery of BMS-986458, a Potent and Selective B-Cell Lymphoma 6 Protein Ligand-Directed Degrader, for the Treatment of B-Cell Non-Hodgkin Lymphoma
2个月前
已完结
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