Lv3
310 积分 2024-09-19 加入
TLR7 Signaling in Lupus B Cells: New Insights into Synergizing Factors and Downstream Signals
4个月前
已完结
Selective IRAK4 degradation, not kinase inhibition, blocks TLR-activated NF-Kb and p38 Signaling leading to broad cytokine inhibition
4个月前
已关闭
Oligonucleotide-based Toll-like Receptor Antagonists and Therapeutic Applications
4个月前
已完结
First‐in‐Human Study of the Safety, Tolerability, Pharmacokinetics, Immunogenicity, and Pharmacodynamics of DS‐7011a, an Anti‐TLR7 Antagonistic Monoclonal Antibody for the Treatment of Systemic Lupus Erythematosus
4个月前
已完结
POS0540 REDUCTION OF B CELL SUBSETS, AUTOANTIBODIES AND DISEASE-RELEVANT PATHWAYS IN IANALUMAB TREATED PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS: FINDINGS FROM A PHASE 2 CLINICAL TRIAL
4个月前
已关闭
Inhibition of Toll-Like Receptor 7 (TLR7) With a Selective Inhibitor of Human TLR7 ST-301 Reverse Lupus Progression in Murine Lupus Models
5个月前
已关闭
Differences in expression of lupus nephritis in New Zealand mixed H-2z homozygous inbred strains of mice derived from New Zealand black and New Zealand white mice. Origins and initial characterization
5个月前
已关闭
Targeting TLR Signaling Cascades in Systemic Lupus Erythematosus and Rheumatoid Arthritis: An Update
6个月前
已完结
Discovery of the TLR7/8 Antagonist MHV370 for Treatment of Systemic Autoimmune Diseases
6个月前
已完结
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