Lv2
106 积分 2021-07-13 加入
Discovery of a Novel Series of Homo sapiens Caseinolytic Protease P Agonists for Colorectal Adenocarcinoma Treatment via ATF3-Dependent Integrated Stress Response
1个月前
已完结
A shape complementarity strategy based on NCA029 enables potent HsClpP agonists for the treatment of small cell lung carcinoma
3个月前
已完结
Design and synthesis of JNK1-targeted PROTACs and research on the activity
3个月前
已完结
Protac synthesized on the basis of azaflavonoid derivatives possesses favorable anti-hepatocellular carcinoma activity
3个月前
已完结
Identification of a novel Azaspirooxindolinone-based PROTAC for selective BTK degradation and enhanced anticancer activity
3个月前
已完结
Discovery of a potent and selective JAK1-targeting PROTAC degrader with anti-tumor activities
3个月前
已完结
Design, synthesis, and bioevaluation of SOS1 PROTACs derived from pyrido[2,3-d]pyrimidin-7-one-based SOS1 inhibitor
3个月前
已完结
Discovery of a proteolysis targeting chimera (PROTAC) as a potent regulator of FOXP3
3个月前
已完结
Novel lipid-mimetic prodrugs delivering active compounds to adipose tissue
3个月前
已完结
Insulin action in the brain regulates mitochondrial stress responses and reduces diet-induced weight gain
3个月前
已完结
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