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22 积分 2021-07-13 加入
Patenting perspective of modulators of ClpP endopeptidase: 2019-present
1天前
待确认
Patenting perspective of modulators of ClpP endopeptidase: 2019-present
1天前
已完结
Balancing stability and activation: A pseudoparabolic activity spectrum guides fatty acid chain length optimization in prodrug-albumin nanoparticles
3个月前
已完结
An oral-to-urinalysis fluorescent prodrug platform for IBD theranostics
3个月前
已完结
A shape complementarity strategy based on NCA029 enables potent HsClpP agonists for the treatment of small cell lung carcinoma
3个月前
已完结
Access to novel potent pleiotropic prodrugs, targeting both butyrylcholinesterase and serotonin reuptake, with anti-amnesic activities in Alzheimer’s disease model
3个月前
已完结
Design, Synthesis, and Biological Evaluation of Novel Activators of Human Caseinolytic Protease P with a Pyrazololactam Scaffold
3个月前
已完结
Development of novel imipridone derivatives with potent anti-cancer activities as human caseinolytic peptidase P (hClpP) activators
3个月前
已完结
Discovery of Orally Bioavailable and Brain-Penetrable Prodrugs of the Potent nSMase2 Inhibitor DPTIP
5个月前
已完结
Novel Diaryl-Substituted Pyrazolo[3,4-d]pyrimidines as Tubulin/CDC5L Dual-Targeting Ligands: Discovery, Potent Antitumor Activity, and Good Metabolic Stability
5个月前
已完结
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