Lv6
2128 积分 2021-05-28 加入
A renaissance in targeting the PI3K/AKT/mTOR pathway
11天前
已完结
Lead Optimization of N-3-Substituted 7-Morpholinotriazolopyrimidines as Dual Phosphoinositide 3-Kinase/Mammalian Target of Rapamycin Inhibitors: Discovery of PKI-402
1个月前
已完结
Bis(morpholino-1,3,5-triazine) Derivatives: Potent Adenosine 5′-Triphosphate Competitive Phosphatidylinositol-3-kinase/Mammalian Target of Rapamycin Inhibitors: Discovery of Compound 26 (PKI-587), a Highly Efficacious Dual Inhibitor
1个月前
已完结
From Lead to Clinical Candidate: Discovery of BMS-986331 as a Potent and Selective N -Formyl Peptide Receptor 2 Agonist
1个月前
已完结
New PROTAC Designs for Targeted Protein Degradation in 2021–2025: Novel E3 Ligases and Pre-PROTACs
1个月前
已完结
Optimization of Covalent 6-Cyanoquinazoline KRAS G12C Inhibitors for the Treatment of Solid Tumors
1个月前
已完结
The Discovery of RGH-706, a Highly Efficacious MCH1 Receptor Antagonist, for the Treatment of Obesity and Insatiable Hunger
1个月前
已完结
Rare Case of Polymorphism in the Binary System of Enantiomers of a Praziquantel Derivative
1个月前
已完结
An Improved Commercial Process for the Preparation of Lifitegrast
1个月前
已完结
The Discovery of GS-1291269: A Neutral Ketohexokinase (KHK) Inhibitor with an Unusual Thietane Amine Functional Group
2个月前
已完结
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