Lv7
4170 积分 2021-05-28 加入
Discovery of Imidazo[2,1- b ][1,3,4]thiadiazole-Based MNK Inhibitors with Anti-inflammatory Efficacy via Dual Suppression of eIF4E Phosphorylation and NF-κB Signaling
9天前
已完结
Discovery of a Highly Potent and Selective mTOR Inhibitor that Strongly Suppresses Glioblastoma Multiforme Cell Growth
9天前
已完结
Discovery of FLC-8 as the First Covalent FLT3 Inhibitor Targeting Cys807 for FLT3 Mutant Acute Myeloid Leukemia
9天前
已完结
Optimization of METTL3 Inhibitors for the Treatment of Solid Tumors and AML
9天前
已完结
Discovery of Highly Potent and Selective IKZF2 Degraders for Cancer Immunotherapy
9天前
已完结
Development of Benzimidazole-Based BZ-30 as an Orally Bioavailable Broad-Spectrum Inhibitor of SARS-CoV-2
9天前
已完结
Design, Synthesis, and Biological Evaluation of Pyrimido[4,5- b ]indole Derivatives with Potent Activity against Multidrug-Resistant Gram-Negative Bacteria
9天前
已完结
Discovery of Non-prostanoid EP4 Agonists for the Treatment of Inflammatory Bowel Disease
9天前
已完结
Discovery and Evaluation of a PROTAC Degrader Targeting SAMHD1 for the Treatment of Pulmonary Fibrosis
9天前
已完结
Optimization of Covalent 6-Cyanoquinazoline KRAS G12C Inhibitors for the Treatment of Solid Tumors
9天前
已完结
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