Lv2
160 积分 2021-05-29 加入
Safe and Effective Sarcoma Therapy through Bispecific Targeting of EGFR and uPAR
21天前
已完结
Broadening Degrader Therapeutics: Keap1 PROTACs, Antimalarial Hybrids, and PLK1 Inhibition of NLRP3 Inflammasomes
1个月前
已关闭
New PROTAC Designs for Targeted Protein Degradation in 2021–2025: Novel E3 Ligases and Pre-PROTACs
3个月前
已完结
Discovery of the First Potent PI3K/mTOR Dual-Targeting PROTAC Degrader for Efficient Modulation of the PI3K/AKT/mTOR Pathway
6个月前
已完结
Development of Small Molecule Chimeras That Recruit AhR E3 Ligase to Target Proteins
6个月前
已完结
Functional Characterization of Pathway Inhibitors for the Ubiquitin-Proteasome System (UPS) as Tool Compounds for CRBN and VHL-Mediated Targeted Protein Degradation
7个月前
已完结
Progress in RAS‐targeted therapeutic strategies: From small molecule inhibitors to proteolysis targeting chimeras
10个月前
已完结
Harnessing the SPOP E3 Ubiquitin Ligase via a Bridged Proteolysis Targeting Chimera (PROTAC) Strategy for Targeted Protein Degradation
10个月前
已完结
P4ward: An Automated Modeling Platform for Protac Ternary Complexes
10个月前
已完结
Structure-Based Design of Transport-Specific Multitargeted One-Carbon Metabolism Inhibitors in Cytosol and Mitochondria
10个月前
已完结
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