Lv3
238 积分 2025-03-04 加入
Discovery of CP-690,550: A Potent and Selective Janus Kinase (JAK) Inhibitor for the Treatment of Autoimmune Diseases and Organ Transplant Rejection
1天前
待确认
KRAS G12C mutated NSCLC and bladder cancer xenografts treated with sotorasib and adagrasib in combination with mTOR inhibitors show improved antitumor activity of nab-sirolimus vs everolimus
2个月前
已完结
Potential role for TL1A, the new TNF-family member and potent costimulator of IFN-γ, in mucosal inflammation
4个月前
已完结
Discovery of the Clinical Candidate IDOR-1117-2520: A Potent and Selective Antagonist of CCR6 for Autoimmune Diseases
6个月前
已完结
A cereblon-based glue degrader of NEK7 regulates NLRP3 inflammasome in a context-dependent manner
6个月前
已完结
Selective and Potent Molecular Glue Degraders for NIMA‐Related Kinase 7
6个月前
已完结
NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux
6个月前
已完结
Selective and Potent Molecular Glue Degraders for NIMA‐Related Kinase 7
6个月前
已完结
Discovery of AMG 193, an MTA-Cooperative PRMT5 Inhibitor for the Treatment of MTAP-Deleted Cancers
11个月前
已完结
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