Lv42
672 积分 2022-05-06 加入
ZBTB11 depletion targets metabolic vulnerabilities in KRAS inhibitor-resistant PDAC
2小时前
求助中
Interleukin-4 promotes the clearance of amyloid-β by monocyte through enhancing the recognition and intracellular processing of amyloid-β
5天前
已完结
Discovery of AK-1690: A Potent and Highly Selective STAT6 PROTAC Degrader
5天前
已完结
The IL-4 receptor alpha-chain cytoplasmic domain is sufficient for activation of JAK-1 and STAT6 and the induction of IL-4-specific gene expression
5天前
已完结
Targeting Innate Immune Checkpoint TREX1 is a Safe and Effective Immunotherapeutic Strategy in Cancer
6天前
已完结
Molecular glues that facilitate RAS binding to PI3Kα promote glucose uptake without insulin
8天前
已完结
Skp2 is required for survival of aberrantly proliferating Rb1-deficient cells and for tumorigenesis in Rb1+/− mice
12天前
已关闭
Identification of the antidepressive properties of C1, a specific inhibitor of Skp2, in mice
12天前
已完结
Targeting the untargetable: RB1-deficient tumours are vulnerable to Skp2 ubiquitin ligase inhibition
12天前
已完结
Discovery of Novel 1,3-Diphenylpyrazine Derivatives as Potent S-Phase Kinase-Associated Protein 2 (Skp2) Inhibitors for the Treatment of Cancer
13天前
已完结
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