Lv5
832 积分 2022-05-06 加入
A selective BCL-XL PROTAC degrader achieves safe and potent antitumor activity
5天前
已完结
Nanoliposomal Bcl-xL proteolysis-targeting chimera enhances anti-cancer effects on cervical and breast cancer without on-target toxicities
5天前
已完结
The MEK-RAF molecular glue IK-595 has potent antitumor activity across RAS/MAPK pathway-altered cancers
6天前
已完结
A Keap1-recruiting BRD4 degrader offers a single-molecular polypharmacology approach for the treatment of metabolic dysfunction-associated steatohepatitis
10天前
已完结
Knockdown of Circ_CCNB2 Sensitizes Prostate Cancer to Radiation Through Repressing Autophagy by the miR-30b-5p/KIF18A Axis
12天前
已完结
Structural and Physicochemical Features of Oral PROTACs
15天前
已完结
Tumor Treating Fields therapy with standard systemic therapy versus standard systemic therapy alone in metastatic non-small-cell lung cancer following progression on or after platinum-based therapy (LUNAR): a randomised, open-label, pivotal phase 3 study
1个月前
已完结
Structural Insights into the Development of Inhibitors Against Cancer-Specific Mutations of PI3Kα
1个月前
已完结
Coproporphyrin I as an in vitro fluorescent probe to measure OATP1B1 transport activity
2个月前
已完结
Sotorasib versus docetaxel for previously treated non-small-cell lung cancer with KRAS(G12C) mutation: a randomised, open-label, phase 3 trial
2个月前
已完结
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