Lv5
1092 积分 2022-05-06 加入
Discovery of the First-in-Class Protein Arginine Methyltransferase 1 PROTAC Degrader
20天前
已完结
Crystal Structure Prediction Synergizes with Crystallization Tendency Analysis: A Case Study in Polymorph Screening of a Novel PRMT5 Inhibitor
25天前
已完结
A rapid imaging-based screen for induced-proximity degraders identifies a potent degrader of oncoprotein SKP2
1个月前
已完结
Discovery of Potent, Highly Selective, and Orally Bioavailable MTA Cooperative PRMT5 Inhibitors with Robust In Vivo Antitumor Activity
1个月前
已完结
Discovery and Evaluation of a PROTAC Degrader Targeting SAMHD1 for the Treatment of Pulmonary Fibrosis
1个月前
已完结
Mechanisms of Response and Tolerance to Active RAS Inhibition in KRAS -Mutant Non–Small Cell Lung Cancer
1个月前
已完结
Setidegrasib in Advanced Non–Small-Cell Lung Cancer and Pancreatic Cancer
1个月前
已完结
Setidegrasib in Advanced Non–Small-Cell Lung Cancer and Pancreatic Cancer
1个月前
已完结
Discovery of Daraxonrasib (RMC-6236), a Potent and Orally Bioavailable RAS(ON) Multi-selective, Noncovalent Tri-complex Inhibitor for the Treatment of Patients with Multiple RAS-Addicted Cancers
1个月前
已完结
Aberrant epigenetic regulation of bromodomain Brd4 in human colon cancer
1个月前
已完结
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