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30 积分 2021-11-09 加入
Design of Potent mRNA Decapping Scavenger Enzyme (DcpS) Inhibitors with Improved Physicochemical Properties To Investigate the Mechanism of Therapeutic Benefit in Spinal Muscular Atrophy (SMA)
8天前
已完结
Degron-independent recruitment of KAT2A expands the target space of CRBN molecular glues
9天前
已完结
The DcpS inhibitor RG3039 improves motor function in SMA mice
10天前
已完结
Discovery of Milvexian, a High-Affinity, Orally Bioavailable Inhibitor of Factor XIa in Clinical Studies for Antithrombotic Therapy
14天前
已完结
Design and Synthesis of an Orally Bioavailable and Selective Peptide Epoxyketone Proteasome Inhibitor (PR-047)
14天前
已完结
1,2-Epoxycycloalkanes: Substrates and inhibitors of microsomal and cytosolic epoxide hydrolases in mouse liver
1个月前
已完结
From membrane to mineralization: the curious case of the ABCC6 transporter
1个月前
已完结
Chasing molecular glue degraders: screening approaches
1个月前
已完结
Mining the CRBN target space redefines rules for molecular glue–induced neosubstrate recognition
1个月前
已完结
Molecular glue degraders of HuR suppress BRAF-mutant colorectal cancer
1个月前
已完结
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