Lv11
10 积分 2021-11-09 加入
Structure-Guided Discovery of Aminoquinazolines as Brain-Penetrant and Selective LRRK2 Inhibitors
1小时前
待确认
Discovery of MK-1468: A Potent, Kinome-Selective, Brain-Penetrant Amidoisoquinoline LRRK2 Inhibitor for the Potential Treatment of Parkinson’s Disease
1小时前
已完结
Discovery of Novel Potent and Safe Immunoproteasome Inhibitors with Bridged Ring for Anti-Inflammatory Therapy
1小时前
已完结
Innovative Medicinal Chemistry Strategies for Improving Target Binding Kinetics in Drug Discovery
3天前
已完结
Identification of Novel Series of Potent and Selective Relaxin Family Peptide Receptor 1 (RXFP1) Agonists
5天前
已完结
Discovery of Clinical Candidate AZD5462, a Selective Oral Allosteric RXFP1 Agonist for Treatment of Heart Failure
5天前
已完结
Overcoming Challenges in the Metabolism of Peptide Therapeutics: Strategies and Case Studies for Clinical Success
6天前
已完结
Development of a Direct-to-Biology Platform to Discover Potent MNK Inhibitors
6天前
已完结
Structural and functional diversity calls for a new classification of ABC transporters
7天前
已完结
Structural and Functional Characterization of the ABCC6 Transporter in Hepatic Cells: Role on PXE, Cancer Therapy and Drug Resistance
13天前
已完结
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