Lv11
40 积分 2021-11-09 加入
Mining the CRBN target space redefines rules for molecular glue–induced neosubstrate recognition
4天前
已完结
Molecular glue degraders of HuR suppress BRAF-mutant colorectal cancer
5天前
已完结
Toxicity and Teratogenicity of Optical Isomers of Thalidomide
15天前
已完结
Strengths, Weaknesses, Opportunities, and Potential Threat Analysis of Targeting Leucine-Rich Repeat Kinase 2 for Parkinson’s Disease Treatment: Status Quo and Quo Vadis
1个月前
已完结
Discovery of a 3-(4-Pyrimidinyl) Indazole (MLi-2), an Orally Available and Selective Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitor that Reduces Brain Kinase Activity
1个月前
已完结
Discovery and Optimization of Potent, Selective, and Brain-Penetrant 1-Heteroaryl-1H-Indazole LRRK2 Kinase Inhibitors for the Treatment of Parkinson’s Disease
1个月前
已完结
Discovery of Potent, Selective, CNS-Penetrant Macrocyclic LRRK2 Inhibitors for the Treatment of Parkinson’s Disease
1个月前
已完结
Structure-Guided Discovery of Aminoquinazolines as Brain-Penetrant and Selective LRRK2 Inhibitors
1个月前
已完结
Discovery of MK-1468: A Potent, Kinome-Selective, Brain-Penetrant Amidoisoquinoline LRRK2 Inhibitor for the Potential Treatment of Parkinson’s Disease
1个月前
已完结
Discovery of Novel Potent and Safe Immunoproteasome Inhibitors with Bridged Ring for Anti-Inflammatory Therapy
1个月前
已完结
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