Lv1
10 积分 2021-11-09 加入
Structure-Based Optimization of a Novel Class of Aldehyde Dehydrogenase 1A (ALDH1A) Subfamily-Selective Inhibitors as Potential Adjuncts to Ovarian Cancer Chemotherapy
4天前
已完结
Stepwise Evolution of Fragment Hits against MAPK Interacting Kinases 1 and 2
4天前
已完结
Oxetanes in Drug Discovery Campaigns
4天前
已完结
TRI-611, a selective, brain-penetrant molecular glue degrader of ALK
29天前
已完结
Novel Macrocyclic NLRP3 Inhibitors
1个月前
已完结
Design of Potent mRNA Decapping Scavenger Enzyme (DcpS) Inhibitors with Improved Physicochemical Properties To Investigate the Mechanism of Therapeutic Benefit in Spinal Muscular Atrophy (SMA)
1个月前
已完结
Degron-independent recruitment of KAT2A expands the target space of CRBN molecular glues
1个月前
已完结
The DcpS inhibitor RG3039 improves motor function in SMA mice
1个月前
已完结
Discovery of Milvexian, a High-Affinity, Orally Bioavailable Inhibitor of Factor XIa in Clinical Studies for Antithrombotic Therapy
2个月前
已完结
Design and Synthesis of an Orally Bioavailable and Selective Peptide Epoxyketone Proteasome Inhibitor (PR-047)
2个月前
已完结
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