Lv75
4650 积分 2022-02-18 加入
PEGylation of Dipeptide Linker Improves Therapeutic Index and Pharmacokinetics of Antibody-Drug Conjugates
15天前
已完结
SMP-656: A Self-Catalyzed Ring-Opening Hydrolysis Linker-Based ADC with Enhanced Stability and Antitumor Efficacy
17天前
已完结
A Science-Based Proposal for the Identification Threshold of Organic Impurities in Drug–Linker Intermediates Used to Produce Antibody–Drug Conjugates
18天前
已完结
Targeting Multiple KRAS Mutations with High-Affinity Macrocyclic Inhibitors: From Discovery to Preclinical Validation
20天前
已完结
Multivalent linkers: A growing trend in antibody–drug conjugate development
20天前
已完结
Enzymatic assay based platform for the chiral purity assessment of cathepsin-cleavable antibody-drug conjugate linker-drugs
20天前
已完结
Lead Optimization of Multimutant KRAS Switch-II Pocket Macrocyclic Inhibitors via Isosteric Replacement to Improve ADME and Oral Exposure
21天前
已完结
A dual-payload heavy-chain antibody conjugate boosting bystander effect for heterogeneous tumor therapy
1个月前
已完结
Benzylamine‐Based Organoselenium Compounds as Glutathione Peroxidase Mimics: Antioxidant and Antibacterial Agents
1个月前
已完结
Recent Advances in Glutarimide Chemistry for Cereblon-Mediated Targeted Protein Degradation: Developments in Synthesis and Diversification
1个月前
已完结
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