Lv8
6800 积分 2022-07-14 加入
Small-molecule probes from bench to bedside: advancing molecular analysis of drug–target interactions toward precision medicine
6个月前
已完结
Preparation of 5-Hydroxy-2-iodopyridine: A Refutation of Earlier Reports
6个月前
已完结
Direct deaminative functionalization with N-nitroamines
6个月前
已完结
A selective BCL-XL PROTAC degrader achieves safe and potent antitumor activity
8个月前
已完结
Discovery of Pyridine-2-Carboxamides Derivatives as Potent and Selective HPK1 Inhibitors for the Treatment of Cancer
8个月前
已完结
Assembly of α‐(Hetero)aryl Nitriles via Copper‐Catalyzed Coupling Reactions with (Hetero)aryl Chlorides and Bromides
8个月前
已完结
A Selective and Orally Bioavailable Quinoline-6-Carbonitrile-Based Inhibitor of CDK8/19 Mediator Kinase with Tumor-Enriched Pharmacokinetics
8个月前
已完结
Regioselective Functionalization of 4-Methyl-1H-indole for Scalable Synthesis of 2-Cyano-5-formyl-4-methyl-1H-indole
9个月前
已完结
KLF2 maintains lineage fidelity and suppresses CD8 T cell exhaustion during acute LCMV infection
9小时前
待审核
Semi‐Ionic C‐F Bonds Modulate Hydrogen Dynamics for Selective CO 2 ‐to‐CH 4 Electroreduction on Carbon Quantum Dots
10小时前
已采纳
Axion insulator, Weyl points, quantum anomalous Hall effect, and magnetic topological phase transition in Eu3In2As4
15小时前
待审核
Isolated and H2-reduced Anderson clusters catalyse low-temperature hydrogenation of CO2to methanol
16小时前
待审核
Organocatalytic Asymmetric Formal Aza‐[3+3]Cyclo‐additions of 3‐Aminobenzofuran with α,β‐Unsaturated Aldehydes
16小时前
已采纳
An antiswelling biodegradable hydrogel reshapes electro-microenvironment to drive endogenous neuroregeneration after brain defect
17小时前
待审核
SIRT2-mediated deacetylation of LCK governs the magnitude of T cell receptor signaling
17小时前
已采纳
Hollow MnO2 as a tumor-microenvironment-responsive biodegradable nano-platform for combination therapy favoring antitumor immune responses
18小时前
待审核
Synergistic Copper‐Coordination/Glutathione Reduction Drives an In Situ Type II‐to‐Type I Photodynamic Switch in Iridium‐Based Photosensitizer Nanocomposites for Potentiated Cancer Immunotherapy
18小时前
已采纳