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110 积分 2025-05-06 加入
Cathepsin B-Labile Dipeptide Linkers for Lysosomal Release of Doxorubicin from Internalizing Immunoconjugates: Model Studies of Enzymatic Drug Release and Antigen-Specific In Vitro Anticancer Activity
9天前
已完结
Synthesis and Evaluation of Camptothecin Antibody–Drug Conjugates
1个月前
已完结
β-glucuronidase-triggered ortho-hydroxyl-mediated cyclization strategy for the efficient delivery of phenolic payloads in antibody-drug conjugates
1个月前
已关闭
Discovery and Preclinical Evaluation of PBX-7016, a Methylenedioxy-Camptothecin Payload for Antibody-Drug Conjugates with Enhanced Therapeutic Potential
4个月前
已完结
Preclinical Studies of OBI-999: A Novel Globo H–Targeting Antibody–Drug Conjugate
4个月前
已完结
A GGCT fluorogenic probe: design, synthesis and application to cancer-related cells
5个月前
已完结
Introducing a squaramide-based self-immolative spacer for controlled drug release
5个月前
已完结
A trifunctional self-immolative spacer enables drug release with two non-sequential enzymatic cleavages
5个月前
已完结
Development of Substituted Phenyl Dihydrouracil as the Novel Achiral Cereblon Ligands for Targeted Protein Degradation
7个月前
已完结
Abstract 596: Development and assessment of a novel tumor microenvironment activable linker (TMALIN) ADC platform for solid tumor treatments
7个月前
已完结
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