Lv1
36 积分 2024-02-23 加入
Asymmetric Synthesis of the cis-1,2-Diaryltetralin Vepdegestrant Core via an Enantioselective Intramolecular Corey-Chaykovsky Epoxidation
1个月前
已完结
Targeting cyclin-dependent kinases in cancer: emerging therapeutics and clinical strategies
2个月前
已完结
A Type II CDK6 Degrader Enables Cellular Targeting beyond the Limits of Type II Inhibition
2个月前
已完结
Misconceptions among medicinal chemists regarding ADME and PK optimization
4个月前
已完结
Real-world effectiveness comparison of first-line palbociclib, ribociclib or abemaciclib plus endocrine therapy in advanced HR-positive/HER2-negative BC patients: results from the multicenter PALMARES-2 study
4个月前
已完结
Hijacking ERAD for targeted degradation of transmembrane proteins
5个月前
已完结
Expanding the targeted protein degradation approach with small molecule chimeras directed to the 26S proteasome
5个月前
已完结
Structure-Based Discovery of HS34: A Highly Selective and Orally Bioavailable CDK9 Inhibitor for Triple-Negative Breast Cancer
6个月前
已完结
Metabolic Stability of Fluorinated Small Molecules: A Physical Organic Chemistry Perspective
6个月前
已完结
Discovery of AK-1690: A Potent and Highly Selective STAT6 PROTAC Degrader
7个月前
已完结
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