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36 积分 2024-02-23 加入
Structure-Based Discovery of HS34: A Highly Selective and Orally Bioavailable CDK9 Inhibitor for Triple-Negative Breast Cancer
17小时前
待确认
Metabolic Stability of Fluorinated Small Molecules: A Physical Organic Chemistry Perspective
7天前
已完结
Discovery of AK-1690: A Potent and Highly Selective STAT6 PROTAC Degrader
1个月前
已完结
A small-molecule VHL molecular glue degrader for cysteine dioxygenase 1
1个月前
已完结
Discovery of Selective and Orally Bioavailable Heterobifunctional Degraders of Cyclin-Dependent Kinase 2
3个月前
已完结
Optimizing Shape Complementarity Enables the Discovery of Potent Tricyclic BCL6 Inhibitors
7个月前
已完结
Ribociclib plus endocrine therapy for premenopausal women with hormone-receptor-positive, advanced breast cancer (MONALEESA-7): a randomised phase 3 trial
7个月前
已完结
Third-generation CDK inhibitors: A review on the synthesis and binding modes of Palbociclib, Ribociclib and Abemaciclib
7个月前
已完结
Discovery of an In Vivo Chemical Probe for BCL6 Inhibition by Optimization of Tricyclic Quinolinones
7个月前
已完结
DNA-Templated Spatially Controlled Proteolysis Targeting Chimera for Cyclin D1–CDK4/6 Complex Protein Degradation
7个月前
已完结
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