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20 积分 2024-01-26 加入
CC-90009, a Novel Cereblon E3 Ligase Modulator, Targets GSPT1 for Degradation to Induce Potent Tumoricidal Activity Against Acute Myeloid Leukemia (AML)
11小时前
求助中
Caspase-8 Regulates the Antimyeloma Activity of Bortezomib and Lenalidomide
6天前
已完结
Discovery of a dual WDR5 and Ikaros PROTAC degrader as an anti-cancer therapeutic
22天前
已完结
Induction of Apoptosis and Activation of Endoplasmic Reticulum Stress by SJ6986 in Diffuse Large B-cell Lymphoma
1个月前
已完结
Bifunctional chemical probes inducing protein-protein interactions
1个月前
已完结
Discovery of degrader for FLT3, GSPT1 and IKZF1/3 proteins merging PROTAC and molecular glue targeting FLT3-ITD mutant acute myeloid leukemia
1个月前
已完结
Discovery of a dual-target CRBN-mediated degrader for IKZF1/3 and GSPT1 proteins
1个月前
已完结
Discovery of highly potent dual GSPT1/BRD4 degraders with anti-AML activity
1个月前
已完结
Frizzled and LRP5/6 Receptors for Wnt/β-Catenin Signaling
1个月前
已完结
Crystal structure of a β-catenin/axin complex suggests a mechanism for the β-catenin destruction complex
1个月前
已完结
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