Lv62
2940 积分 2025-07-09 加入
Discovery of a PROTAC targeting ALK with in vivo activity
刚刚
求助中
Structure-based discovery of SIAIS001 as an oral bioavailability ALK degrader constructed from Alectinib
2分钟前
待确认
Analysis of lorlatinib analogs reveals a roadmap for targeting diverse compound resistance mutations in ALK-positive lung cancer
9分钟前
待确认
Discovery of orally bioavailable ALK PROTACs based ceritinib against ALK positive cancers
33分钟前
待确认
Synthesis and Bioevaluation of 3-(Arylmethylene)indole Derivatives: Discovery of a Novel ALK Modulator with Antiglioblastoma Activities
56分钟前
待确认
Distal C(sp 3 )-H Amidation via Ind*Rh III Catalyzed Nitrene Transfer
3个月前
已完结
Enantioselective Pd-catalysed nucleophilic C(sp3)–H (radio)fluorination
3个月前
已完结
Enantioselective C–H Activation for the Construction of Chiral Tertiary Fluorides via Migrative Carbofluorination
3个月前
已完结
Palladium-Catalyzed β-C(sp3)–H Nitrooxylation of Ketones and Amides Using Practical Oxidants
3个月前
已完结
Ligand‐Enabled β‐C(sp3)−H Lactamization of Tosyl‐Protected Aliphatic Amides Using a Practical Oxidant
3个月前
已完结