Lv11
38 积分 2024-11-19 加入
Decarboxylation of the Catalytic Lysine Residue by the C5α-Methyl-Substituted Carbapenem NA-1-157 Leads to Potent Inhibition of the OXA-58 Carbapenemase
19天前
已完结
Restricted Rotational Flexibility of the C5α-Methyl-Substituted Carbapenem NA-1-157 Leads to Potent Inhibition of the GES-5 Carbapenemase
19天前
已完结
Development of bisubstrate analog inhibitors of aspartate N‐acetyltransferase, a critical brain enzyme
20天前
已完结
Celastrol Targets Cullin-Associated and Neddylation-Dissociated 1 to Prevent Fibroblast–Myofibroblast Transformation against Pulmonary Fibrosis
21天前
已完结
Precise Conformational Control Yielding Highly Potent and Exceptionally Selective BRD4 Degraders with Strong Antitumor Activity
26天前
已完结
Synthesis, in silico studies and biological evaluation of novel thiazolidinone[5,4-d] isoxazole derivatives as antidiabetic agents
1个月前
已完结
Characterization of P-type H+-ATPase Pma1 inhibitors that extend chronological lifespan in fission yeast
1个月前
已完结
In vitro identification of oridonin hybrids as potential anti-TNBC agents inducing cell cycle arrest and apoptosis by regulation of p21, γH2AX and cleaved PARP
1个月前
已完结
Bicyclo[m.n.k]alkane Building Blocks as Promising Benzene and Cycloalkane Isosteres: Multigram Synthesis, Physicochemical and Structural Characterization
1个月前
已完结
Catalytic asymmetric total synthesis of diazabicyclooctane β-lactamase inhibitors avibactam and relebactam
1个月前
已完结
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