Lv11
92 积分 2024-12-07 加入
The ubiquitin ligase MDM2 sustains STAT5 stability to control T cell-mediated antitumor immunity
6小时前
待确认
Novel Triazoloquinoxaline-Based Tubulin Polymerization Inhibitor Induces Necroptosis and Significantly Inhibits Metastatic Melanoma Tumor Growth
21天前
已完结
Design, synthesis, and biological evaluation of novel diphenylamine derivatives as tubulin polymerization inhibitors targeting the colchicine binding site
1个月前
已完结
Optimization of Benzamide Derivatives as Potent and Orally Active Tubulin Inhibitors Targeting the Colchicine Binding Site
1个月前
已完结
Discovery of a Covalent Inhibitor Targeting the PHGDH Dimer Interface with Antitumor Efficacy
3个月前
已关闭
Multi-target pyrazolopyrimidine-coumarin derivatives as potent CA IX/XII and tubulin polymerization inhibitors: Design, synthesis, and biological evaluation
3个月前
已关闭
Discovery of quinoxaline-chalcone derivatives as covalent colchicine binding site inhibitors for breast and fibrosarcoma treatment
5个月前
已完结
Design, synthesis, and structure–activity relationship study of novel plinabulin derivatives as anti-tumor agents based on the co-crystal structure
5个月前
已完结
Development of a New Benzophenone–Diketopiperazine-Type Potent Antimicrotubule Agent Possessing a 2-Pyridine Structure
5个月前
已完结
Multimechanistic Conjugates Based on Melampomagnolide B and 10-HCPT/SN-38: Novel Antitumor Agents for Colorectal Cancer Therapy
5个月前
已完结
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