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96 积分 2024-12-07 加入
Design, synthesis, and biological evaluation of novel diphenylamine derivatives as tubulin polymerization inhibitors targeting the colchicine binding site
6天前
已完结
Optimization of Benzamide Derivatives as Potent and Orally Active Tubulin Inhibitors Targeting the Colchicine Binding Site
6天前
已完结
Discovery of a Covalent Inhibitor Targeting the PHGDH Dimer Interface with Antitumor Efficacy
1个月前
已关闭
Multi-target pyrazolopyrimidine-coumarin derivatives as potent CA IX/XII and tubulin polymerization inhibitors: Design, synthesis, and biological evaluation
1个月前
已关闭
Discovery of quinoxaline-chalcone derivatives as covalent colchicine binding site inhibitors for breast and fibrosarcoma treatment
3个月前
已完结
Design, synthesis, and structure–activity relationship study of novel plinabulin derivatives as anti-tumor agents based on the co-crystal structure
3个月前
已完结
Development of a New Benzophenone–Diketopiperazine-Type Potent Antimicrotubule Agent Possessing a 2-Pyridine Structure
4个月前
已完结
Multimechanistic Conjugates Based on Melampomagnolide B and 10-HCPT/SN-38: Novel Antitumor Agents for Colorectal Cancer Therapy
4个月前
已完结
Marine natural product-inspired 2-(3,4,5-trimethoxybenzoyl)quinazolin-4(3H)-one derivative CHNQD-01522: A novel anti-hepatocellular carcinoma agent targeting colchicine binding site of microtubule
4个月前
已完结
Discovery of Novel Furan-type Phenylahistin Derivatives for Anticancer through P53-Mediated Mitochondrial Apoptosis and Microtubule Inhibition
4个月前
已完结
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