Lv54
1298 积分 2022-10-27 加入
Mechanism of MEK inhibition determines efficacy in mutant KRAS- versus BRAF-driven cancers
11天前
已完结
Synthesis of tertiary alkyl amines via photoinduced copper-catalysed nucleophilic substitution
14天前
已完结
Discovery of AZD8421: A Potent CDK2 Inhibitor with Selectivity Against Other CDK Family Members and the Human Kinome
14天前
已完结
Synthetic lethality in cancer drug discovery: challenges and opportunities
14天前
已完结
Oxidations of Alcohols, Aldehydes, and Diols Using NaBr and Selectfluor
1个月前
已完结
Abstract LB008: ATV-1601, a potent and selective allosteric inhibitor of AKT1E17K, demonstrates profound and durable regressions in multiple patient and cell derived xenograft models
1个月前
已关闭
Mutant-selective AKT inhibition through lysine targeting and neo-zinc chelation
1个月前
已完结
Discovery of Clinical Candidate NTQ1062 as a Potent and Bioavailable Akt Inhibitor for the Treatment of Human Tumors
1个月前
已完结
Discovery of 4-Amino-N-[(1S)-1-(4-chlorophenyl)-3-hydroxypropyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide (AZD5363), an Orally Bioavailable, Potent Inhibitor of Akt Kinases
1个月前
已完结
Decarboxylative Cross-Coupling: A Radical Tool In Medicinal Chemistry
1个月前
已完结
皖公网安备34019202002308
