Lv63
2038 积分 2022-10-27 加入
Daraxonrasib (RMC-6236) pharmacokinetics: impact of transporters and drug-metabolizing enzymes on a first-in-class pan-RAS molecular glue
1天前
已完结
Stereoselective Access to Tetra‐ and Tri‐Substituted Fluoro‐ and Chloro‐Borylalkenes via Boron‐Wittig Reaction
16天前
已完结
Design, Synthesis, and Biological Evaluation of 5-Formyl-pyrrolo[3,2-b]pyridine-3-carboxamides as New Selective, Potent, and Reversible-Covalent FGFR4 Inhibitors
2个月前
已完结
Discovery of Pyrrolopyrazine Carboxamide Derivatives as Potent and Selective FGFR2/3 Inhibitors that Overcome Mutant Resistance
3个月前
已完结
Ligandless Microwave-Assisted Pd/Cu-Catalyzed Direct Arylation of Oxazoles
3个月前
已完结
A General Pd-Catalyzed C2–H Arylation of Benzoxazoles with Highly Sterically Congested Aryl Chlorides Enabled by a Fittingly Tuned Ligand
3个月前
已完结
Highly Enantioselective Chemoenzymatic and Kilogram-Scale Process Development of ( S )-3-Bromo-2-(1-methoxyethyl)pyridine
3个月前
已完结
Chemical remodeling of a cellular chaperone to target the active state of mutant KRAS
5个月前
已完结
The MEK–RAF molecular glue IK-595 has potent antitumor activity across RAS/MAPK pathway-altered cancers
5个月前
已完结
Highly Efficient Suzuki–Miyaura Polymerization Enabled by Direct Transmetalation with Boronic Esters
5个月前
已完结
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