Lv6
1798 积分 2022-10-27 加入
Design, Synthesis, and Biological Evaluation of 5-Formyl-pyrrolo[3,2-b]pyridine-3-carboxamides as New Selective, Potent, and Reversible-Covalent FGFR4 Inhibitors
6天前
已完结
Discovery of Pyrrolopyrazine Carboxamide Derivatives as Potent and Selective FGFR2/3 Inhibitors that Overcome Mutant Resistance
24天前
已完结
Ligandless Microwave-Assisted Pd/Cu-Catalyzed Direct Arylation of Oxazoles
1个月前
已完结
A General Pd-Catalyzed C2–H Arylation of Benzoxazoles with Highly Sterically Congested Aryl Chlorides Enabled by a Fittingly Tuned Ligand
1个月前
已完结
Highly Enantioselective Chemoenzymatic and Kilogram-Scale Process Development of ( S )-3-Bromo-2-(1-methoxyethyl)pyridine
1个月前
已完结
Chemical remodeling of a cellular chaperone to target the active state of mutant KRAS
3个月前
已完结
The MEK–RAF molecular glue IK-595 has potent antitumor activity across RAS/MAPK pathway-altered cancers
3个月前
已完结
Highly Efficient Suzuki–Miyaura Polymerization Enabled by Direct Transmetalation with Boronic Esters
3个月前
已完结
Catalytic 2-Ethylhexanoic Acid Promotes Mild Miyaura Borylations
4个月前
已完结
Enantioselective Total Synthesis of (−)-Cyathin B2: A Desymmetric Double-Allylboration Approach
4个月前
已完结