Lv11
16 积分 2026-01-21 加入
Abstract B123: Mechanism of action of ivonescimab (AK112/SMT112): a first-in-class tetravalent Fc-silent bispecific antibody with dual blockade of PD-1 and VEGF that promotes cooperative biological effects
7小时前
已完结
Unlike LGR4, LGR5 potentiates Wnt–β-catenin signaling without sequestering E3 ligases
24天前
已完结
RSPO2-Based Peptibodies Conjugated with Pyrrolobenzodiazepine Dimer or Camptothecin Analogs Demonstrate Potent Antitumor Activity by Targeting the Three Receptors LGR4/5/6 in Colorectal Cancer and Neuroblastoma
1个月前
已完结
Discovery of the first dual PD-L1/JAK inhibitor with enhanced in vivo antitumor immunity
1个月前
已完结
Functional patient-derived organoid screenings identify MCLA-158 as a therapeutic EGFR × LGR5 bispecific antibody with efficacy in epithelial tumors
5个月前
已完结
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