Lv1
66 积分 2025-01-25 加入
Mitochondrial pyruvate carrier 1 regulates fatty acid synthase lactylation and mediates treatment of nonalcoholic fatty liver disease
3个月前
已完结
Lactylation-Driven YTHDC1 Alleviates MASLD by Suppressing PTPN22-Mediated Dephosphorylation of NLRP3
3个月前
已完结
Oxidative Stress-Responsive Intracellular Regulation Specific for the Angiostatic Form of Human Tryptophanyl-tRNA Synthetase
6个月前
已完结
A Medicinal Chemistry Perspective on Lactate Dehydrogenase: Current Status and Future Directions
7个月前
已完结
A Dual-Target and Dual-Mechanism Design Strategy by Combining Inhibition and Degradation Together
7个月前
已完结
Molecular glue degrader function of SPOP enhances STING-dependent immunotherapy efficacy in melanoma models
8个月前
已完结
Discovery of
9个月前
已完结
Lactate Metabolic Reprogramming Mediated by CircRNA-LDHA Complex Facilitates Innate Immune Evasion of Liver Cancer
9个月前
已关闭
Design and Discovery of Preclinical Candidate LYG-409 as a Highly Potent and Selective GSPT1 Molecular Glue Degraders
1年前
已完结
Lysosome-dependent p300/FOXP3 degradation and limits Treg cell functions and enhances targeted therapy against cancers
1年前
已完结
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